| Literature DB >> 24764198 |
F Etcheverrigaray1, M Grall-Bronnec2, M-C Blanchet2, P Jolliet1, C Victorri-Vigneau1.
Abstract
Ibuprofen is currently widely prescribed and has not been reported to produce dependence. We report the case of a 17-year old patient who presented many positive psychic symptoms related to a pharmacological dependence. During the treatment, she adjusted herself posology as she developed withdrawal symptoms. Pharmacological evidences (effect on COX-1 and COX-2, FAAH and PPARs) allow us to formulate hypotheses explaining this effect. © Georg Thieme Verlag KG Stuttgart · New York.Entities:
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Year: 2014 PMID: 24764198 DOI: 10.1055/s-0034-1371868
Source DB: PubMed Journal: Pharmacopsychiatry ISSN: 0176-3679 Impact factor: 5.788