Literature DB >> 24763069

Validity and reliability of the neuropsychiatric inventory questionnaire version in patients with stroke or transient ischemic attack having cognitive impairment.

Adrian Wong1, Sheung-Tak Cheng2, Eugene S K Lo3, Pauline W L Kwan3, Lorraine S N Law3, Anne Y Y Chan3, Lawrence Ka-Sing Wong3, Vincent Mok4.   

Abstract

This study examined the validity and reliability of the Neuropsychiatric Inventory Questionnaire version (NPI-Q), a proxy-reported format of the interview-based NPI, in assessing neuropsychiatric symptoms in 173 patients with stroke or transient ischemic attack (TIA) having cognitive impairment. The NPI-Q was validated against the NPI as a gold standard. Informants took approximately 7 minutes to complete the NPI-Q. Bland-Altman analysis revealed a bias of 0.7 points, with 95% limits of agreement between -8.6 and 10.0 between the total symptom scores of the NPI and NPI-Q. The NPI-Q correlated significantly with the NPI in individual and total symptom scores and caregiver distress scores. In predicting presence of symptoms on the NPI, the NPI-Q yielded, on average, sensitivity of 74.1% and specificity of 79.5%. On the NPI-Q, informants tended to overreport symptoms in patients with less severe symptoms but underreport with increasing symptom severity. Internal consistency of the NPI-Q was acceptable (Cronbach's α = 0.756). One-week test-retest reliability of the NPI-Q was excellent (intraclass correlation coefficient = .990). The NPI-Q is a valid and reliable instrument for screening neuropsychiatric symptoms in patients with stroke and TIA.
© The Author(s) 2014.

Entities:  

Keywords:  behavioral and psychological symptoms of dementia; clinical assessment; neuropsychiatric inventory questionnaire; stroke; vascular cognitive impairment; vascular dementia

Mesh：

Year:  2014        PMID： 24763069     DOI： 10.1177/0891988714532017

Source DB:  PubMed          Journal:  J Geriatr Psychiatry Neurol        ISSN： 0891-9887            Impact factor:   2.680


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