Literature DB >> 2476296

Midlatency auditory evoked responses: differential abnormality of P1 in Alzheimer's disease.

J S Buchwald1, R J Erwin, S Read, D Van Lancker, J L Cummings.   

Abstract

The human 'P1' middle latency evoked potential is postulated to be generated in the thalamus by a cholinergic component of the ascending reticular activating system. To test the hypothesis that P1 and its generator substrate are abnormal in Alzheimer's disease (AD), a disorder of marked cholinergic deficiency, recordings of middle latency responses to click stimuli were carried out. Comparisons between the AD and age-matched control groups indicated normal auditory brain-stem and Pa responses but a significant decrease in P1 amplitude. This P1 abnormality suggests that the midbrain cholinergic cells in AD may be dysfunctional.

Entities:  

Mesh：

Year:  1989        PMID： 2476296     DOI： 10.1016/0168-5597(89)90005-1

Source DB:  PubMed          Journal:  Electroencephalogr Clin Neurophysiol        ISSN： 0013-4694


  9 in total

1.  The auditory P50 component to onset and offset of sound.

Authors:  Hillel Pratt; Arnold Starr; Henry J Michalewski; Naomi Bleich; Nomi Mittelman
Journal:  Clin Neurophysiol       Date:  2007-12-04       Impact factor: 3.708

2.  Long-term deficits of preterm birth: evidence for arousal and attentional disturbances.

Authors:  R Whit Hall; Tiffany Wallace Huitt; Richa Thapa; D Keith Williams; K J S Anand; Edgar Garcia-Rill
Journal:  Clin Neurophysiol       Date:  2008-03-26       Impact factor: 3.708

3.  Arousal and the control of perception and movement.

Authors:  E Garcia-Rill; T Virmani; J R Hyde; S D'Onofrio; S Mahaffey
Journal:  Curr Trends Neurol       Date:  2016

4.  AROUSAL FROM SLICES TO HUMANS: Translational studies on sleep-wake control.

Authors:  N Kezunovic; C Simon; J Hyde; K Smith; P Beck; A Odle; E Garcia-Rill
Journal:  Transl Neurosci       Date:  2010-03-01       Impact factor: 1.757

Review 5.  The pedunculopontine tegmental nucleus: from basic neuroscience to neurosurgical applications: arousal from slices to humans: implications for DBS.

Authors:  Edgar Garcia-Rill; Christen Simon; Kristen Smith; Nebosja Kezunovic; James Hyde
Journal:  J Neural Transm (Vienna)       Date:  2010-10-09       Impact factor: 3.575

6.  Noradrenergic antagonism of the P13 and N40 components of the rat auditory evoked potential.

Authors:  Sarah K Keedy; Megan Marlow-O'Connor; Beth Beenken; Jill Dorflinger; Marc Abel; Roland J Erwin
Journal:  Psychopharmacology (Berl)       Date:  2006-11-10       Impact factor: 4.530

7.  Effects of glutamate receptor agonists on the p13 auditory evoked potential and startle response in the rat.

Authors:  Christen Simon; Tiffany Wallace-Huitt; Priyenka Thapa; Robert D Skinner; Edgar Garcia-Rill
Journal:  Front Neurol       Date:  2011-01-27       Impact factor: 4.003

8.  Diminished n1 auditory evoked potentials to oddball stimuli in misophonia patients.

Authors:  Arjan Schröder; Rosanne van Diepen; Ali Mazaheri; Diamantis Petropoulos-Petalas; Vicente Soto de Amesti; Nienke Vulink; Damiaan Denys
Journal:  Front Behav Neurosci       Date:  2014-04-09       Impact factor: 3.558

9.  Investigating Auditory Electrophysiological Measures of Participants with Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis of Event-Related Potential Studies.

Authors:  Hadeel Y Tarawneh; Wilhelmina H A M Mulders; Hamid R Sohrabi; Ralph N Martins; Dona M P Jayakody
Journal:  J Alzheimers Dis       Date:  2021       Impact factor: 4.472
  9 in total

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