Literature DB >> 24762846

Smoking synthetic marijuana leads to self-mutilation requiring bilateral amputations.

Karim A Meijer, Russell R Russo, Dhaval V Adhvaryu.   

Abstract

Synthetic cannabinoids have become a worldwide epidemic because they provide a sometimes legal, easily accessible, and presumably safe alternative to marijuana. Recently published reports have linked acute psychosis, myocardial infarctions, convulsions, self-harm, and even terrorist organizations to these designer substances. This case report outlines the first reported case of Black Diamond, a synthetic cannabis, leading to a self-inflicted burn to the bilateral upper extremities requiring a transradial amputation of the right arm and a toe transfer procedure of the left hand after loss of all digits. The patient presented to the emergency department with self-inflicted fourth-degree burns to the bilateral hands and forearms with second-degree burns of the face, for a total body surface area of 14.5%. The patient was found by firefighters with his hands aflame on his kitchen stove. With no previous medical or psychiatric history and collateral information to confirm the patient's mental status prior to use of Black Diamond, the patient's acute psychotic episode was attributed to Black Diamond. After multiple procedures and a lengthy recovery, the patient completed his post-graduate education and entered the professional world. As orthopedic surgeons, we should be involved in educating the public on the harm of these designer drugs, including self-mutilation. The popularity of synthetic drugs in the United States will continue to present a major challenge to all health care providers. Orthopedists are on the front lines of this epidemic because these drugs push patients into risky, traumatic behavior. Copyright 2014, SLACK Incorporated.

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Year:  2014        PMID: 24762846     DOI: 10.3928/01477447-20140401-62

Source DB:  PubMed          Journal:  Orthopedics        ISSN: 0147-7447            Impact factor:   1.390


  15 in total

Review 1.  Synthetic cannabinoids 2015: An update for pediatricians in clinical practice.

Authors:  Daniel Castellanos; Leonard M Gralnik
Journal:  World J Clin Pediatr       Date:  2016-02-08

Review 2.  Synthetic Pot: Not Your Grandfather's Marijuana.

Authors:  Benjamin M Ford; Sherrica Tai; William E Fantegrossi; Paul L Prather
Journal:  Trends Pharmacol Sci       Date:  2017-02-02       Impact factor: 14.819

Review 3.  The Bridge Between Classical and "Synthetic"/Chemical Psychoses: Towards a Clinical, Psychopathological, and Therapeutic Perspective.

Authors:  Laura Orsolini; Stefania Chiappini; Duccio Papanti; Domenico De Berardis; John M Corkery; Fabrizio Schifano
Journal:  Front Psychiatry       Date:  2019-11-20       Impact factor: 4.157

Review 4.  Care of the Patient Using Cannabis.

Authors:  Arthur Robin Williams; Kevin P Hill
Journal:  Ann Intern Med       Date:  2020-11-03       Impact factor: 25.391

5.  Cluster of Acute Toxicity from Ingestion of Synthetic Cannabinoid-Laced Brownies.

Authors:  Adebisi I Obafemi; Kurt Kleinschmidt; Collin Goto; Drew Fout
Journal:  J Med Toxicol       Date:  2015-12

6.  Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays.

Authors:  T W Grim; A J Morales; M M Gonek; J L Wiley; B F Thomas; G W Endres; L J Sim-Selley; D E Selley; S S Negus; A H Lichtman
Journal:  J Pharmacol Exp Ther       Date:  2016-08-17       Impact factor: 4.030

Review 7.  Adverse Effects of Synthetic Cannabinoids: Management of Acute Toxicity and Withdrawal.

Authors:  Ziva D Cooper
Journal:  Curr Psychiatry Rep       Date:  2016-05       Impact factor: 5.285

8.  The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity.

Authors:  Jose Orsini; Christa Blaak; Eric Tam; Salil Rajayer; Joaquin Morante; Angela Yeh; Ashvin Butala
Journal:  Case Rep Crit Care       Date:  2015-12-14

9.  "Spice" (Synthetic Marijuana) Induced Acute Myocardial Infarction: A Case Series.

Authors:  E Ul Haq; A Shafiq; A A Khan; A A Awan; S Ezad; W J Minteer; B Omar
Journal:  Case Rep Cardiol       Date:  2017-07-26

Review 10.  Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health.

Authors:  Aviv M Weinstein; Paola Rosca; Liana Fattore; Edythe D London
Journal:  Front Psychiatry       Date:  2017-08-23       Impact factor: 4.157

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