Literature DB >> 2475908

Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth.

P W Finch1, J S Rubin, T Miki, D Ron, S A Aaronson.   

Abstract

Keratinocyte growth factor (KGF) is a human mitogen that is specific for epithelial cells. The complementary DNA sequence of KGF demonstrates that it is a member of the fibroblast growth factor family. The KGF transcript was present in stromal cells derived from epithelial tissues. By comparison with the expression of other epithelial cell mitogens, only KGF, among known human growth factors, has the properties of a stromal mediator of epithelial cell proliferation.

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Year:  1989        PMID: 2475908     DOI: 10.1126/science.2475908

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  221 in total

Review 1.  Function of intestinal gammadelta T cells.

Authors:  R Boismenu
Journal:  Immunol Res       Date:  2000       Impact factor: 2.829

2.  Keratinocyte Growth Factor Stimulates Macrophage Inflammatory Protein 3α and Keratinocyte-derived Chemokine Secretion by Mouse Uterine Epithelial Cells.

Authors:  Severina N Haddad; Charles R Wira
Journal:  Am J Reprod Immunol       Date:  2010-09       Impact factor: 3.886

3.  Possible involvement of myofibroblasts in cellular recovery of uranyl acetate-induced acute renal failure in rats.

Authors:  D F Sun; Y Fujigaki; T Fujimoto; K Yonemura; A Hishida
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

4.  Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin.

Authors:  A Mansukhani; P Dell'Era; D Moscatelli; S Kornbluth; H Hanafusa; C Basilico
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

5.  Aggregation pathway of recombinant human keratinocyte growth factor and its stabilization.

Authors:  B L Chen; T Arakawa; C F Morris; W C Kenney; C M Wells; C G Pitt
Journal:  Pharm Res       Date:  1994-11       Impact factor: 4.200

6.  Expression of pro-inflammatory markers by human dermal fibroblasts in a three-dimensional culture model is mediated by an autocrine interleukin-1 loop.

Authors:  Daniela Kessler-Becker; Thomas Krieg; Beate Eckes
Journal:  Biochem J       Date:  2004-04-15       Impact factor: 3.857

7.  Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells.

Authors:  Seema Saksena; Shubha Priyamvada; Anoop Kumar; Maria Akhtar; Vikas Soni; Arivarasu Natarajan Anbazhagan; Anas Alakkam; Waddah A Alrefai; Pradeep K Dudeja; Ravinder K Gill
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2013-01-17       Impact factor: 4.052

8.  Keratinocyte growth factor induces proliferation of hepatocytes and epithelial cells throughout the rat gastrointestinal tract.

Authors:  R M Housley; C F Morris; W Boyle; B Ring; R Biltz; J E Tarpley; S L Aukerman; P L Devine; R H Whitehead; G F Pierce
Journal:  J Clin Invest       Date:  1994-11       Impact factor: 14.808

Review 9.  Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas.

Authors:  R S Morrison; F Yamaguchi; H Saya; J M Bruner; A M Yahanda; L A Donehower; M Berger
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

10.  Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy.

Authors:  G Yan; Y Fukabori; G McBride; S Nikolaropolous; W L McKeehan
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

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