Literature DB >> 24756815

Phenolic constituents from stem bark of Erythrina poeppigiana and their inhibitory activity on human glyoxalase I.

Kiyomi Hikita1, Hitoshi Tanaka, Tomiyasu Murata, Kuniki Kato, Miyuki Hirata, Tatsuko Sakai, Norio Kaneda.   

Abstract

A novel isoflavone, erythgianin A (1), along with nine known compounds 2-10, was isolated from the stem bark of Erythrina poeppigiana (Leguminosae). The unusual isoflavone structure of 1, possessing a highly oxidized 3″,4″-dihydroxy-2″-hydroxymethyl-2″-methyl-2″,3″-dihydropyrano substituent, was determined on the basis of spectroscopic analyses. All of the isolated compounds were evaluated for their in vitro inhibitory activity toward human glyoxalase I. Among the isolates, isolupalbigenin (10) with two prenyl groups showed the highest inhibitory activity.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 24756815     DOI： 10.1007/s11418-014-0834-z

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  17 in total

1.  Isoflavonoids from Ficus benjamina and their inhibitory activity on BACE1.

Authors:  Jingqiu Dai; Dai Shen; Wesley Y Yoshida; Stephen M Parrish; Philip G Williams
Journal:  Planta Med       Date:  2012-07-04       Impact factor: 3.352

2.  The mechanism of action of glyoxalase.

Authors:  E RACKER
Journal:  J Biol Chem       Date:  1951-06       Impact factor: 5.157

Review 3.  The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.

Authors:  P J Thornalley
Journal:  Biochem J       Date:  1990-07-01       Impact factor: 3.857

4.  Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis.

Authors:  H Sakamoto; T Mashima; A Kizaki; S Dan; Y Hashimoto; M Naito; T Tsuruo
Journal:  Blood       Date:  2000-05-15       Impact factor: 22.113

5.  Studies on the inhibition of glyoxalase I by S-substituted glutathiones.

Authors:  R Vince; S Daluge; W B Wadd
Journal:  J Med Chem       Date:  1971-05       Impact factor: 7.446

6.  Prenylated flavonoids in the roots of yellow lupin.

Authors:  S Tahara; Y Katagiri; J L Ingham; J Mizutani
Journal:  Phytochemistry       Date:  1994-07       Impact factor: 4.072

7.  Glyoxalase I from mouse liver.

Authors:  B Oray; S J Norton
Journal:  Methods Enzymol       Date:  1982       Impact factor: 1.600

Review 8.  Glyoxalase in tumourigenesis and multidrug resistance.

Authors:  Paul J Thornalley; Naila Rabbani
Journal:  Semin Cell Dev Biol       Date:  2011-02-18       Impact factor: 7.727

9.  Erythrina poeppigiana-derived phytochemical exhibiting antimicrobial activity against Candida albicans and methicillin-resistant Staphylococcus aureus.

Authors:  M Sato; H Tanaka; R Yamaguchi; T Oh-Uchi; H Etoh
Journal:  Lett Appl Microbiol       Date:  2003       Impact factor: 2.858

10.  An arylbenzofuran and four isoflavonoids from the roots of Erythrina poeppigiana.

Authors:  Hitoshi Tanaka; Tomoko Oh-Uchi; Hideo Etoh; Magoichi Sako; Masaru Sato; Toshio Fukai; Yoichi Tateishi
Journal:  Phytochemistry       Date:  2003-07       Impact factor: 4.072
View more
  1 in total

1.  Potent apoptosis-inducing activity of erypoegin K, an isoflavone isolated from Erythrina poeppigiana, against human leukemia HL-60 cells.

Authors:  Kiyomi Hikita; Natsuki Hattori; Aya Takeda; Yuko Yamakage; Rina Shibata; Saori Yamada; Kuniki Kato; Tomiyasu Murata; Hitoshi Tanaka; Norio Kaneda
Journal:  J Nat Med       Date:  2017-11-18       Impact factor: 2.343
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.