Literature DB >> 24756720

TRPM7.

Andrea Fleig1, Vladimir Chubanov.   

Abstract

The channel kinases TRPM6 and TRPM7 are fusion proteins with an ion transport domain and an enzymatically active kinase domain. TRPM7 has been found in every mammalian tissue investigated to date. The two-in-one protein structure, the ubiquitous expression profile, and the protein's unique biophysical characteristics that enable divalent ion transport involve TRPM7 in a plethora of (patho)physiological processes. With its prominent role in cellular and systemic magnesium homeostasis, TRPM7 emerges as a key player in embryonic development, global ischemia, cardiovascular disease, and cancer.

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Year:  2014        PMID： 24756720      PMCID： PMC5663634          DOI： 10.1007/978-3-642-54215-2_21

Source DB:  PubMed          Journal:  Handb Exp Pharmacol        ISSN： 0171-2004


  143 in total

1.  TRPM7 is a stretch- and swelling-activated cation channel involved in volume regulation in human epithelial cells.

Authors:  Tomohiro Numata; Takahiro Shimizu; Yasunobu Okada
Journal:  Am J Physiol Cell Physiol       Date:  2006-08-30       Impact factor: 4.249

2.  Molecular determinants of Mg2+ and Ca2+ permeability and pH sensitivity in TRPM6 and TRPM7.

Authors:  Mingjiang Li; Jianyang Du; Jianmin Jiang; William Ratzan; Li-Ting Su; Loren W Runnels; Lixia Yue
Journal:  J Biol Chem       Date:  2007-06-28       Impact factor: 5.157

3.  TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx.

Authors:  Jian-Peng Chen; Yi Luan; Chang-Xuan You; Xiao-Hua Chen; Rong-Cheng Luo; Rong Li
Journal:  Cell Calcium       Date:  2010-04-03       Impact factor: 6.817

4.  Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors:  O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal:  Pflugers Arch       Date:  1981-08       Impact factor: 3.657

5.  Differential effects of cyclosporin A and tacrolimus on magnesium influx in Caco2 cells.

Authors:  Elodie Gouadon; Florence Lecerf; Michèle German-Fattal
Journal:  J Pharm Pharm Sci       Date:  2012       Impact factor: 2.327

6.  Does a higher ratio of serum calcium to magnesium increase the risk for postmenopausal breast cancer?

Authors:  Abe E Sahmoun; Brij B Singh
Journal:  Med Hypotheses       Date:  2010-04-03       Impact factor: 1.538

7.  Identification of the phosphorylation sites on intact TRPM7 channels from mammalian cells.

Authors:  Tae Yong Kim; Seok Kyo Shin; Min-Young Song; Ji Eun Lee; Kang-Sik Park
Journal:  Biochem Biophys Res Commun       Date:  2011-12-26       Impact factor: 3.575

8.  Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia.

Authors:  Vladimir Chubanov; Siegfried Waldegger; Michael Mederos y Schnitzler; Helga Vitzthum; Martin C Sassen; Hannsjörg W Seyberth; Martin Konrad; Thomas Gudermann
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-19       Impact factor: 11.205

9.  Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel.

Authors:  Takayuki Teramoto; Laura A Sternick; Eriko Kage-Nakadai; Shirine Sajjadi; Jakub Siembida; Shohei Mitani; Kouichi Iwasaki; Eric J Lambie
Journal:  PLoS One       Date:  2010-03-08       Impact factor: 3.240

10.  Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation.

Authors:  Jie Jiang; Ming-Hua Li; Koichi Inoue; Xiang-Ping Chu; Joshua Seeds; Zhi-Gang Xiong
Journal:  Cancer Res       Date:  2007-11-15       Impact factor: 12.701
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  44 in total

Review 1.  Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

Authors:  Nathan R Tykocki; Erika M Boerman; William F Jackson
Journal:  Compr Physiol       Date:  2017-03-16       Impact factor: 9.090

2.  A TRPM4-dependent current in murine renal primary cilia.

Authors:  Richard J Flannery; Nancy K Kleene; Steven J Kleene
Journal:  Am J Physiol Renal Physiol       Date:  2015-08-19

Review 3.  Transient Receptor Potential Channels in Microglia: Roles in Physiology and Disease.

Authors:  Santiago Echeverry; María Juliana Rodriguez; Yolima P Torres
Journal:  Neurotox Res       Date:  2016-06-03       Impact factor: 3.911

4.  Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.

Authors:  Thomas Gudermann; Susanne Muehlich; Sandra Voringer; Laura Schreyer; Wiebke Nadolni; Melanie A Meier; Katharina Woerther; Constanze Mittermeier; Silvia Ferioli; Stephan Singer; Kerstin Holzer; Susanna Zierler; Vladimir Chubanov; Bernhard Liebl
Journal:  Oncogene       Date:  2019-12-16       Impact factor: 9.867

5.  The TRPM7 channel kinase regulates store-operated calcium entry.

Authors:  Malika Faouzi; Tatiana Kilch; F David Horgen; Andrea Fleig; Reinhold Penner
Journal:  J Physiol       Date:  2017-03-10       Impact factor: 5.182

Review 6.  Role of the chanzyme TRPM7 in the nervous system in health and disease.

Authors:  Nashat Abumaria; Wei Li; Andrew N Clarkson
Journal:  Cell Mol Life Sci       Date:  2019-05-09       Impact factor: 9.261

7.  The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins.

Authors:  Sayuri Suzuki; Annette Lis; Carsten Schmitz; Reinhold Penner; Andrea Fleig
Journal:  Cell Mol Life Sci       Date:  2018-03-02       Impact factor: 9.261

Review 8.  Electrophysiological properties of NG2(+) cells: Matching physiological studies with gene expression profiles.

Authors:  Valerie A Larson; Ye Zhang; Dwight E Bergles
Journal:  Brain Res       Date:  2015-09-15       Impact factor: 3.252

9.  TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity.

Authors:  Alayna Mellott; Jananie Rockwood; Tetyana Zhelay; Charles Tuan Luu; Taku Kaitsuka; J Ashot Kozak
Journal:  Pflugers Arch       Date:  2020-09-22       Impact factor: 3.657

10.  Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.

Authors:  Sebastian Schäfer; Silvia Ferioli; Thomas Hofmann; Susanna Zierler; Thomas Gudermann; Vladimir Chubanov
Journal:  Pflugers Arch       Date:  2015-12-16       Impact factor: 3.657
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