Literature DB >> 24756711

The TRPV4 channel.

Anna Garcia-Elias1, Sanela Mrkonjić, Carole Jung, Carlos Pardo-Pastor, Rubén Vicente, Miguel A Valverde.   

Abstract

The widely distributed TRPV4 cationic channel participates in the transduction of both physical (osmotic, mechanical, and heat) and chemical (endogenous, plant-derived, and synthetic ligands) stimuli. In this chapter we will review TRPV4 expression, biophysics, structure, regulation, and interacting partners as well as physiological and pathological insights obtained in TRPV4 animal models and human genetic studies.

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Year:  2014        PMID： 24756711     DOI： 10.1007/978-3-642-54215-2_12

Source DB:  PubMed          Journal:  Handb Exp Pharmacol        ISSN： 0171-2004


  64 in total

1.  Tripping out on TRPV4.

Authors:  Friedrich C Luft
Journal:  J Mol Med (Berl)       Date:  2015-12       Impact factor: 4.599

2.  A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.

Authors:  Stephen H Loukin; Jinfeng Teng; Ching Kung
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-13       Impact factor: 11.205

3.  L596-W733 bond between the start of the S4-S5 linker and the TRP box stabilizes the closed state of TRPV4 channel.

Authors:  Jinfeng Teng; Stephen H Loukin; Andriy Anishkin; Ching Kung
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-03       Impact factor: 11.205

Review 4.  Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

Authors:  Nathan R Tykocki; Erika M Boerman; William F Jackson
Journal:  Compr Physiol       Date:  2017-03-16       Impact factor: 9.090

5.  Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch.

Authors:  Jialie Luo; Jing Feng; Guang Yu; Pu Yang; Madison R Mack; Junhui Du; Weihua Yu; Aihua Qian; Yujin Zhang; Shenbin Liu; Shijin Yin; Amy Xu; Jizhong Cheng; Qingyun Liu; Roger G O'Neil; Yang Xia; Liang Ma; Susan M Carlton; Brian S Kim; Kenneth Renner; Qin Liu; Hongzhen Hu
Journal:  J Allergy Clin Immunol       Date:  2017-08-11       Impact factor: 10.793

6.  Oncosis and apoptosis induction by activation of an overexpressed ion channel in breast cancer cells.

Authors:  A A Peters; S Y N Jamaludin; K T D S Yapa; S Chalmers; A P Wiegmans; H F Lim; M J G Milevskiy; I Azimi; F M Davis; K S Northwood; E Pera; D L Marcial; E Dray; N J Waterhouse; P J Cabot; T J Gonda; P A Kenny; M A Brown; K K Khanna; S J Roberts-Thomson; G R Monteith
Journal:  Oncogene       Date:  2017-07-31       Impact factor: 9.867

Review 7.  Ion Channels in Endothelial Responses to Fluid Shear Stress.

Authors:  Kristin A Gerhold; Martin A Schwartz
Journal:  Physiology (Bethesda)       Date:  2016-09

Review 8.  TRP functions in the broncho-pulmonary system.

Authors:  Francesco De Logu; Riccardo Patacchini; Giovanni Fontana; Pierangelo Geppetti
Journal:  Semin Immunopathol       Date:  2016-04-15       Impact factor: 9.623

Review 9.  TRPV4: physiological role and therapeutic potential in respiratory diseases.

Authors:  Neil M Goldenberg; Krishnan Ravindran; Wolfgang M Kuebler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2014-10-24       Impact factor: 3.000

10.  Activation of Transient Receptor Potential Vanilloid 4 Promotes the Proliferation of Stem Cells in the Adult Hippocampal Dentate Gyrus.

Authors:  Yujing Tian; Mengwen Qi; Zhiwen Hong; Yingchun Li; Yibiao Yuan; Yimei Du; Lei Chen; Ling Chen
Journal:  Mol Neurobiol       Date:  2016-09-22       Impact factor: 5.590
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