Literature DB >> 24754044

Exercise improves sexual function in women taking antidepressants: results from a randomized crossover trial.

Tierney Ahrold Lorenz, Cindy May Meston.   

Abstract

BACKGROUND: In laboratory studies, exercise immediately before sexual stimuli improved sexual arousal of women taking antidepressants [1]. We evaluated if exercise improves sexual desire, orgasm, and global sexual functioning in women experiencing antidepressant-induced sexual side effects.
METHODS: Fifty-two women who were reporting antidepressant sexual side effects were followed for 3 weeks of sexual activity only. They were randomized to complete either three weeks of exercise immediately before sexual activity (3×/week) or 3 weeks of exercise separate from sexual activity (3×/week). At the end of the first exercise arm, participants crossed to the other. We measured sexual functioning, sexual satisfaction, depression, and physical health.
RESULTS: Exercise immediately prior to sexual activity significantly improved sexual desire and, for women with sexual dysfunction at baseline, global sexual function. Scheduling regular sexual activity significantly improved orgasm function; exercise did not increase this benefit. Neither regular sexual activity nor exercise significantly changed sexual satisfaction.
CONCLUSIONS: Scheduling regular sexual activity and exercise may be an effective tool for the behavioral management of sexual side effects of antidepressants

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Year:  2014        PMID: 24754044      PMCID: PMC4039497          DOI: 10.1002/da.22208

Source DB:  PubMed          Journal:  Depress Anxiety        ISSN: 1091-4269            Impact factor:   6.505


  38 in total

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Authors:  J F Sallis; W L Haskell; P D Wood; S P Fortmann; T Rogers; S N Blair; R S Paffenbarger
Journal:  Am J Epidemiol       Date:  1985-01       Impact factor: 4.897

2.  Predictors of dropout from cardiac exercise rehabilitation. Ontario Exercise-Heart Collaborative Study.

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3.  Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction.

Authors:  A L Montejo; G Llorca; J A Izquierdo; F Rico-Villademoros
Journal:  J Clin Psychiatry       Date:  2001       Impact factor: 4.384

Review 4.  Strategies for managing antidepressant-induced sexual dysfunction: systematic review of randomised controlled trials.

Authors:  Matthew J Taylor; Lisa Rudkin; Keith Hawton
Journal:  J Affect Disord       Date:  2005-09-12       Impact factor: 4.839

Review 5.  Disorders of orgasm in women.

Authors:  Cindy M Meston; Elaine Hull; Roy J Levin; Marca Sipski
Journal:  J Sex Med       Date:  2004-07       Impact factor: 3.802

6.  Attrition in an exercise intervention: a comparison of early and later dropouts.

Authors:  J A Schmidt; C Gruman; M B King; L I Wolfson
Journal:  J Am Geriatr Soc       Date:  2000-08       Impact factor: 5.562

7.  Autonomic correlates of antidepressant treatment using heart-rate variability analysis.

Authors:  Y Khaykin; P Dorian; B Baker; C Shapiro; P Sandor; D Mironov; J Irvine; D Newman
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8.  Evidence for a curvilinear relationship between sympathetic nervous system activation and women's physiological sexual arousal.

Authors:  Tierney Ahrold Lorenz; Christopher B Harte; Lisa Dawn Hamilton; Cindy M Meston
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9.  Differential effects of sympathetic activation on sexual arousal in sexually dysfunctional and functional women.

Authors:  C M Meston; B B Gorzalka
Journal:  J Abnorm Psychol       Date:  1996-11

10.  Increases in heart rate variability with successful treatment in patients with major depressive disorder.

Authors:  S Balogh; D F Fitzpatrick; S E Hendricks; S R Paige
Journal:  Psychopharmacol Bull       Date:  1993
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  8 in total

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4.  Acute caffeine reverses the disruptive effects of chronic fluoxetine on the sexual behavior of female and male rats.

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6.  Sexual Function and Exercise in Postmenopausal Women Residing in Chalous and Nowshahr, Northern Iran.

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Review 8.  Selective Serotonin Reuptake Inhibitor-Induced Sexual Dysfunction: Current Management Perspectives.

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  8 in total

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