Literature DB >> 24753781

Gross intraoperative evaluation (GIE): a reliable method for the evaluation of surgical margins at partial nephrectomy.

Hasan Yilmaz1, Seyfettin Ciftci2, Levend Ozkan2, Ali Saribacak3, Kursat Yildiz4, Ozdal Dillioglugil2.   

Abstract

To determine the efficacy of a new method called by us as "gross intra-operative evaluation (GIE)" for the assessment of surgical margin (SM) status. A total of 26 consecutive patients operated with cT1a-b renal tumors at a single center were included in this study. After the excision, the tumors were uniformly divided into two halves in the longitudinal axis ex vivo. In this way, margins were exposed for GIE for the evaluation of the safety of SMs. Findings of GIE were compared with the permanent section analysis in terms of SM status. Mean patient age, tumor size and margin thickness was 59 (38-79), 3.1 (1.5-6) cm and 3.7 (0.1-12) mm, respectively. In all patients, GIE showed intact margins and none of the patients had positive SM in the final pathological examination. There was no evidence of local recurrence or distant metastasis with a mean follow-up of 25 (4-104) months. All patients are alive. GIE of resected specimen without FS analysis is a safe and effective method for the evaluation of SMs in partial nephrectomy patients.

Entities:  

Keywords:  Kidney cancer; nephron sparing surgery; partial nephrectomy; surgical margin; tumor bed biopsy

Year:  2014        PMID: 24753781      PMCID: PMC3992426     

Source DB:  PubMed          Journal:  Int J Clin Exp Med        ISSN: 1940-5901


  32 in total

1.  Prospective study of safety margins in partial nephrectomy: intraoperative assessment and contribution of frozen section analysis.

Authors:  Marc-Olivier Timsit; Jean-Philippe Bazin; Nicolas Thiounn; Eric Fontaine; Yves Chrétien; Bertrand Dufour; Arnaud Méjean
Journal:  Urology       Date:  2006-04-25       Impact factor: 2.649

2.  Renal ischaemia: not a problem in laparoscopic partial nephrectomy?

Authors:  Michael Marberger
Journal:  BJU Int       Date:  2007-01       Impact factor: 5.588

3.  A retrospective comparison of 2 methods of intraoperative margin evaluation during partial nephrectomy.

Authors:  Ian S Hagemann; James S Lewis
Journal:  J Urol       Date:  2008-12-13       Impact factor: 7.450

4.  Prognostic importance of resection margin width after nephron-sparing surgery for renal cell carcinoma.

Authors:  Elias A Castilla; Louis S Liou; Neil A Abrahams; Amr Fergany; Lisa A Rybicki; Jonathan Myles; Andrew C Novick
Journal:  Urology       Date:  2002-12       Impact factor: 2.649

5.  Is a 1-CM margin necessary during nephron-sparing surgery for renal cell carcinoma?

Authors:  N Y Piper; J T Bishoff; C Magee; J M Haffron; R C Flanigan; A Mintiens; H P Van Poppel; I M Thompson; W J Harmon
Journal:  Urology       Date:  2001-12       Impact factor: 2.649

6.  Rising incidence of renal cell cancer in the United States.

Authors:  W H Chow; S S Devesa; J L Warren; J F Fraumeni
Journal:  JAMA       Date:  1999-05-05       Impact factor: 56.272

7.  Impact of positive surgical margins in patients undergoing partial nephrectomy for renal cortical tumours.

Authors:  Eric O Kwon; Brett S Carver; Mark E Snyder; Paul Russo
Journal:  BJU Int       Date:  2006-11-28       Impact factor: 5.588

Review 8.  Nephron-sparing surgery for renal cell carcinoma: clinicopathologic features predictive of patient outcome.

Authors:  Kent G Krejci; Michael L Blute; John C Cheville; Thomas J Sebo; Christine M Lohse; Horst Zincke
Journal:  Urology       Date:  2003-10       Impact factor: 2.649

9.  Prospective analysis of multifocality in renal cell carcinoma: influence of histological pattern, grade, number, size, volume and deoxyribonucleic acid ploidy.

Authors:  B A Kletscher; J Qian; D G Bostwick; P E Andrews; H Zincke
Journal:  J Urol       Date:  1995-03       Impact factor: 7.450

10.  Renal hypothermia: in vivo and ex vivo.

Authors:  A C Novick
Journal:  Urol Clin North Am       Date:  1983-11       Impact factor: 2.241

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  1 in total

Review 1.  Laparascopic nephrectomy: different techniques and approaches.

Authors:  Tania González León
Journal:  Curr Urol Rep       Date:  2015-02       Impact factor: 3.092

  1 in total

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