Literature DB >> 24752933

5,10-Methylene-tetrahydrofolate dissociates into tetrahydrofolate and formaldehyde at physiological pH and acidic pH, typical conditions used during sample extraction and LC-MS/MS analysis of biological samples.

Margaretha Jägerstad1, Jelena Jastrebova.   

Abstract

Entities:  

Keywords:  5,10-CH2-H4folate; interconversion; stability

Mesh:

Substances:

Year:  2014        PMID: 24752933     DOI: 10.1002/bmc.3214

Source DB:  PubMed          Journal:  Biomed Chromatogr        ISSN: 0269-3879            Impact factor:   1.902


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  5 in total

1.  An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate.

Authors:  Li Chen; Gregory S Ducker; Wenyun Lu; Xin Teng; Joshua D Rabinowitz
Journal:  Anal Bioanal Chem       Date:  2017-08-10       Impact factor: 4.142

Review 2.  Mass spectrometry imaging of therapeutics from animal models to three-dimensional cell cultures.

Authors:  Xin Liu; Amanda B Hummon
Journal:  Anal Chem       Date:  2015-07-02       Impact factor: 6.986

3.  Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway.

Authors:  Gregory S Ducker; Li Chen; Raphael J Morscher; Jonathan M Ghergurovich; Mark Esposito; Xin Teng; Yibin Kang; Joshua D Rabinowitz
Journal:  Cell Metab       Date:  2016-05-19       Impact factor: 27.287

4.  Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies.

Authors:  Piotr Maj; Adam Jarmuła; Piotr Wilk; Małgorzata Prokopowicz; Wojciech Rypniewski; Zbigniew Zieliński; Anna Dowierciał; Agnieszka Bzowska; Wojciech Rode
Journal:  Int J Mol Sci       Date:  2021-04-30       Impact factor: 5.923

5.  Formaldehyde formation in the glycine cleavage system and its use for an aldolase-based biosynthesis of 1,3-prodanediol.

Authors:  Yingying Xu; Hao Meng; Jie Ren; An-Ping Zeng
Journal:  J Biol Eng       Date:  2020-05-14       Impact factor: 4.355

  5 in total

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