Literature DB >> 24752650

Carbohydrate-based first stereoselective total synthesis of bioactive cytospolide P.

Pathi Suman1, Bhimapaka China Raju.   

Abstract

A facile carbohydrate-based highly stereoselective synthetic route has been developed for the cytospolide P (1) from D-ribose for the first time. Key steps of the synthesis include Wittig homologation, regioselective epoxide ring opening, Sharpless asymmetric epoxidation, Evans aldol reaction, and Yamaguchi macrolactonization.

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Year:  2014        PMID: 24752650     DOI: 10.1039/c4ob00323c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  2 in total

1.  Synthesis and biological evaluation of (-)-kunstleramide and its derivatives.

Authors:  R Venkateshwarlu; B Chinnababu; U Ramulu; K Purushotham Reddy; M Damoder Reddy; P Sowjanya; P Venkateswara Rao; S Aravind
Journal:  Medchemcomm       Date:  2016-12-09       Impact factor: 3.597

2.  Total Synthesis of Cytospolide Q.

Authors:  Shamba Chatterjee; Gour Hari Mandal; Rajib Kumar Goswami
Journal:  ACS Omega       Date:  2018-07-05
  2 in total

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