| Literature DB >> 24752650 |
Pathi Suman1, Bhimapaka China Raju.
Abstract
A facile carbohydrate-based highly stereoselective synthetic route has been developed for the cytospolide P (1) from D-ribose for the first time. Key steps of the synthesis include Wittig homologation, regioselective epoxide ring opening, Sharpless asymmetric epoxidation, Evans aldol reaction, and Yamaguchi macrolactonization.Entities:
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Year: 2014 PMID: 24752650 DOI: 10.1039/c4ob00323c
Source DB: PubMed Journal: Org Biomol Chem ISSN: 1477-0520 Impact factor: 3.876