Literature DB >> 24752309

Design of tetraplex specific ligands: cyclic naphthalene diimide.

Yugo Esaki1, Md Monirul Islam, Satoshi Fujii, Shinobu Sato, Shigeori Takenaka.   

Abstract

Cyclic naphthalene diimide 1 bound to hybrid-type tetraplex DNA from 5'-AGGG(TTAGGG)3-3' (K = 8.6 × 10(6) M(-1)) with 260-fold greater affinity than binding to a double stranded oligonucleotide consisting of 5'-GGG AGG TTT CGC-3' and 3'-CCC TCC AAA GCG-5' (nK = 3.3 × 10(4) M(-1)) with 0.5 μM of IC50 for telomerase activity.

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Year:  2014        PMID： 24752309     DOI： 10.1039/c4cc01005a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation.

Authors:  Xiaojuan Xu; Senzhen Wang; Yuan Chang; Chaochao Ge; Xinna Li; Yongli Feng; Songqiang Xie; Chaojie Wang; Fujun Dai; Wen Luo
Journal:  Medchemcomm       Date:  2018-07-06       Impact factor: 3.597

2.  Naphthalene Diimides Carrying Two β-Cyclodextrins Prefer Telomere RNA G-Quadruplex Recognition.

Authors:  Tingting Zou; Yuka Sato; Shuma Kaneyoshi; Kota Mano; Rui Yasukawa; Yoshifumi Nakano; Satoshi Fujii; Shinobu Sato; Shigeori Takenaka
Journal:  Molecules       Date:  2022-06-23       Impact factor: 4.927

3.  Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin.

Authors:  Francesca Greco; Domenica Musumeci; Nicola Borbone; Andrea Patrizia Falanga; Stefano D'Errico; Monica Terracciano; Ilaria Piccialli; Giovanni Nicola Roviello; Giorgia Oliviero
Journal:  Molecules       Date:  2022-05-07       Impact factor: 4.927

4.  Replication Control of Human Telomere G-Quadruplex DNA by G-Quadruplex Ligands Dependent on Solution Environment.

Authors:  Shuntaro Takahashi; Sudipta Bhowmik; Shinobu Sato; Shigeori Takenaka; Naoki Sugimoto
Journal:  Life (Basel)       Date:  2022-04-07

5.  Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K+ Buffer.

Authors:  Steven T G Street; Donovan N Chin; Gregory J Hollingworth; Monica Berry; Juan C Morales; M Carmen Galan
Journal:  Chemistry       Date:  2017-03-30       Impact factor: 5.236

6.  The Interaction of Cyclic Naphthalene Diimide with G-Quadruplex under Molecular Crowding Condition.

Authors:  Tingting Zou; Shinobu Sato; Rui Yasukawa; Ryusuke Takeuchi; Shunsuke Ozaki; Satoshi Fujii; Shigeori Takenaka
Journal:  Molecules       Date:  2020-02-04       Impact factor: 4.411

7.  Disentangling the Structure-Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs.

Authors:  Chiara Platella; Ettore Napolitano; Claudia Riccardi; Domenica Musumeci; Daniela Montesarchio
Journal:  J Med Chem       Date:  2021-03-22       Impact factor: 7.446
  7 in total

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