Literature DB >> 2475191

A dose-dependent effect of recombinant erythropoietin on the reticulocyte population of rats.

H Eder1, B Rosslenbroich, K Failing.   

Abstract

The effect of human recombinant erythropoietin (rEPO) on the reticulocyte count and the reticulocyte maturation distribution in rats was measured with an automatic reticulocyte analysis system (AURAS). The strongest reaction was found on the third day after a single application of rEPO with respect to reticulocyte count, maturation distribution, and the count of immature reticulocytes. At this time these parameters show a distinct dose dependency. The results indicate a possible basis for a simple rEPO bioassay using normocytemic rats.

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Year:  1989        PMID： 2475191     DOI： 10.1007/bf00320065

Source DB:  PubMed          Journal:  Blut        ISSN： 0006-5242


  11 in total

1.  [Modification of reticulocyte count and distribution of degree of maturity by erythropoietin in the rat].

Authors:  H Eder; U Wiemer
Journal:  Folia Haematol Int Mag Klin Morphol Blutforsch       Date:  1987

2.  Cloning and expression of the human erythropoietin gene.

Authors:  F K Lin; S Suggs; C H Lin; J K Browne; R Smalling; J C Egrie; K K Chen; G M Fox; F Martin; Z Stabinsky
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

3.  [Further studies on the effectiveness of erythropoietin in renal failure (author's transl)].

Authors:  U Essers; W Müller; E Brunner
Journal:  Dtsch Med Wochenschr       Date:  1974-08-09       Impact factor: 0.628

Review 4.  Renal erythropoietin: properties and production.

Authors:  W Jelkmann
Journal:  Rev Physiol Biochem Pharmacol       Date:  1986       Impact factor: 5.545

5.  Control of erythropoietin production.

Authors:  J W Fisher
Journal:  Proc Soc Exp Biol Med       Date:  1983-07

Review 6.  The biogenesis of erythropoietin.

Authors:  A J Erslev; J Caro; G Birgegard; R Silver; O Miller
Journal:  Exp Hematol       Date:  1980       Impact factor: 3.084

7.  Purification of human erythropoietin.

Authors:  T Miyake; C K Kung; E Goldwasser
Journal:  J Biol Chem       Date:  1977-08-10       Impact factor: 5.157

8.  Cloning and expression of human erythropoietin cDNA in Escherichia coli.

Authors:  S Lee-Huang
Journal:  Proc Natl Acad Sci U S A       Date:  1984-05       Impact factor: 11.205

9.  Characterization and biological effects of recombinant human erythropoietin.

Authors:  J C Egrie; T W Strickland; J Lane; K Aoki; A M Cohen; R Smalling; G Trail; F K Lin; J K Browne; D K Hines
Journal:  Immunobiology       Date:  1986-09       Impact factor: 3.144

10.  Isolation and characterization of genomic and cDNA clones of human erythropoietin.

Authors:  K Jacobs; C Shoemaker; R Rudersdorf; S D Neill; R J Kaufman; A Mufson; J Seehra; S S Jones; R Hewick; E F Fritsch
Journal:  Nature       Date:  1985 Feb 28-Mar 6       Impact factor: 49.962
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  3 in total

1.  [Automated microfluorometric absolute count and maturation analysis of reticulocytes].

Authors:  H Eder; H Fritsche
Journal:  Klin Wochenschr       Date:  1989-10-17

2.  Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats.

Authors:  Chanil Moon; Melissa Krawczyk; Dongchoon Ahn; Ismayil Ahmet; Doojin Paik; Edward G Lakatta; Mark I Talan
Journal:  Proc Natl Acad Sci U S A       Date:  2003-09-19       Impact factor: 11.205

3.  A re-assessment of erythropoietin as a neuroprotective agent following rat spinal cord compression or contusion injury.

Authors:  Alberto Pinzon; Alexander Marcillo; Diego Pabon; Helen M Bramlett; Mary Bartlett Bunge; W Dalton Dietrich
Journal:  Exp Neurol       Date:  2008-07-14       Impact factor: 5.330
  3 in total

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