Literature DB >> 24750625

Complexation of carbendazim with hydroxypropyl-β-cyclodextrin to improve solubility and fungicidal activity.

Xia Ge1, Zheng Huang, Shilong Tian, Yulong Huang, Chaozhen Zeng.   

Abstract

The effect of hydroxypropyl-β-cyclodextrin (HPβCD) on the improvement of the solubility and fungicidal activity of carbendazim (MBC) has been investigated. The inclusion complexation of HPβCD with MBC has been prepared and characterized by phase solubility diagram, fluorescence, (1)H NMR, ROESY and FT-IR spectra. The stoichiometric ratio and stability constant were determined by Job's plot and phase solubility studies, respectively. The inclusion complex MBC·HPβCD has exhibited different properties from MBC. The obtained inclusion complex was found to significantly improve the water solubility of MBC. In addition, the biological activity indicated that the complex displayed the better fungicidal activity than MBC. The present study provided useful information for a more rational application of MBC.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 24750625     DOI: 10.1016/j.carbpol.2012.02.072

Source DB:  PubMed          Journal:  Carbohydr Polym        ISSN: 0144-8617            Impact factor:   9.381


  6 in total

1.  Mobility and sorption assessment of selected pesticides in alluvial aquifer.

Authors:  Nevena V Živančev; Srđan R Kovačević; Tanja T Radović; Marina M Radišić; Milan A Dimkić
Journal:  Environ Sci Pollut Res Int       Date:  2019-08-02       Impact factor: 4.223

2.  Binding of sulfamethazine to β-cyclodextrin and methyl-β-cyclodextrin.

Authors:  Ariana Zoppi; Alicia Delrivo; Virginia Aiassa; Marcela Raquel Longhi
Journal:  AAPS PharmSciTech       Date:  2013-04-19       Impact factor: 3.246

Review 3.  Encapsulation of biocides by cyclodextrins: toward synergistic effects against pathogens.

Authors:  Véronique Nardello-Rataj; Loïc Leclercq
Journal:  Beilstein J Org Chem       Date:  2014-11-07       Impact factor: 2.883

4.  Gallic acid/hydroxypropyl-β-cyclodextrin complex: Improving solubility for application on in vitro/ in vivo Candida albicans biofilms.

Authors:  Guilherme Rodrigues Teodoro; Aline Vidal Lacerda Gontijo; Aline Chiodi Borges; Márcia Hiromi Tanaka; Gabriela de Morais Gouvêa Lima; Marcos José Salvador; Cristiane Yumi Koga-Ito
Journal:  PLoS One       Date:  2017-07-11       Impact factor: 3.240

5.  Therapeutic efficacy of an injectable formulation of purinostat mesylate in SU-DHL-6 tumour model.

Authors:  Zejiang Zhu; Jiaolin Wen; Yaohui Xu; Heying Pei; Dan Li; Minghai Tang; Peng Bai; Jun He; Zhuang Yang; Lijuan Chen
Journal:  Ann Med       Date:  2022-12       Impact factor: 4.709

6.  Polymeric and Solid Lipid Nanoparticles for Sustained Release of Carbendazim and Tebuconazole in Agricultural Applications.

Authors:  Estefânia Vangelie Ramos Campos; Jhones Luiz de Oliveira; Camila Morais Gonçalves da Silva; Mônica Pascoli; Tatiane Pasquoto; Renata Lima; P C Abhilash; Leonardo Fernandes Fraceto
Journal:  Sci Rep       Date:  2015-09-08       Impact factor: 4.379

  6 in total

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