Literature DB >> 24750225

The natural history of multifocal atrial rhythms in elderly outpatients: insights from the "Ikaria study".

George Lazaros1, Christina Chrysohoou, Evaggelos Oikonomou, Dimitrios Tsiachris, Savvas Mazaris, Erifili Venieri, Kostas Zisimos, Marina Zaromytidou, Maria Kariori, Stamatis Kioufis, Christos Pitsavos, Christodoulos Stefanadis.   

Abstract

BACKGROUND: Multifocal atrial tachycardias confer an adverse prognosis in hospitalized patients. We assessed the prognostic impact of multifocal atrial rhythms (MARs-either chaotic atrial rhythm or multifocal atrial tachycardia/bradycardia) in very elderly outpatients.
METHODS: One hundred ten subjects aged 60-74 years, 112 aged 75-89 years, and 61 over 90 years old, were enrolled and prospectively evaluated. Several demographic and clinical characteristic were recorded in all individuals.
RESULTS: A high prevalence of MARs was detected in the study population (namely, 6%), which in subjects >90 years was even higher (15%). Individuals with MARs were older, more often female and less active. In multivariate analysis, independent predictors of MARs were age (OR = 1.07, 95% CI: 1.02-1.13, P = 0.01) and female sex (OR = 4.77, 95% CI: 1.23-18.48, P = 0.02). The mortality rate during the follow-up period was 8.4% without differences between age groups (P = 0.209). In particular, mortality rate was 6% in individuals with MARs and 9% in those without (P = 0.72). Mortality was associated with age (OR 1.07, 95% CI: 1.02-1.12, P = 0.005) and history of cardiovascular disease at baseline (OR 4.57, 95% CI: 1.87-11.2 P = 0.001).
CONCLUSIONS: Contrary to hospitalized individuals with multifocal atrial tachycardias, MARs were not associated with increased mortality in elderly outpatients in this study.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  Ikaria study; electrocardiography; multifocal atrial rhythms; nonagenariars; prognosis

Mesh:

Year:  2014        PMID: 24750225      PMCID: PMC6932063          DOI: 10.1111/anec.12165

Source DB:  PubMed          Journal:  Ann Noninvasive Electrocardiol        ISSN: 1082-720X            Impact factor:   1.468


  20 in total

1.  Population ageing in the United States of America: implications for public programmes.

Authors:  Joshua M Wiener; Jane Tilly
Journal:  Int J Epidemiol       Date:  2002-08       Impact factor: 7.196

2.  Unveiling the secrets of longevity: the Ikaria study.

Authors:  Christodoulos I Stefanadis
Journal:  Hellenic J Cardiol       Date:  2011 Sep-Oct

Review 3.  Aging and the cardiovascular system.

Authors:  Apostolos Karavidas; George Lazaros; Dimitris Tsiachris; Vlassios Pyrgakis
Journal:  Hellenic J Cardiol       Date:  2010 Sep-Oct

4.  Evidence supporting a new rate threshold for multifocal atrial tachycardia.

Authors:  Seema A Kothari; Sirin Apiyasawat; Navaid Asad; David H Spodick
Journal:  Clin Cardiol       Date:  2005-12       Impact factor: 2.882

Review 5.  Multifocal atrial tachycardia: mechanisms, clinical correlates, and treatment.

Authors:  D L Scher; E L Arsura
Journal:  Am Heart J       Date:  1989-09       Impact factor: 4.749

6.  Chaotic atrial rhythm.

Authors:  R Berlinerblau; W Feder
Journal:  J Electrocardiol       Date:  1972       Impact factor: 1.438

7.  Multifocal atrial tachycardia (chaotic atrial tachycardia). Clinical associations and significance.

Authors:  M J Lipson; S Naimi
Journal:  Circulation       Date:  1970-09       Impact factor: 29.690

8.  Coronary heart disease and atrial fibrillation: the Framingham Study.

Authors:  W B Kannel; R D Abbott; D D Savage; P M McNamara
Journal:  Am Heart J       Date:  1983-08       Impact factor: 4.749

9.  Multifocal atrial arrhythmia--a frequent misdiagnosis? A correlative study using the computerized ECG.

Authors:  P Varriale; W David; B E Chryssos
Journal:  Clin Cardiol       Date:  1992-05       Impact factor: 2.882

10.  Multifocal atrial tachycardia.

Authors:  K Wang; B L Goldfarb; F L Gobel; H G Richman
Journal:  Arch Intern Med       Date:  1977-02
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  2 in total

1.  Clinical Implication of Multifocal Atrial Tachycardia in Children for Pediatric Cardiologist.

Authors:  June Huh
Journal:  Korean Circ J       Date:  2018-02       Impact factor: 3.243

2.  The Complexity of Pediatric Multifocal Atrial Tachycardia and Its Prognostic Factors.

Authors:  Seung Min Baek; Hyun Chung; Mi Kyoung Song; Eun Jung Bae; Gi Beom Kim; Chung Il Noh
Journal:  Korean Circ J       Date:  2018-02       Impact factor: 3.243

  2 in total

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