Literature DB >> 24749829

Interexaminer reproducibility of optical coherence tomography for measuring the tear film meniscus.

Handan Canan1, Rana Altan-Yaycioglu, Burak Ulas, Selcuk Sizmaz, Muge Coban-Karatas.   

Abstract

PURPOSE: New optical coherence tomography (OCT) devices with anterior segment module are able to measure the tear meniscus height (TMH) and tear meniscus area (TMA). Since the borders of the area and the height are to be marked by an examiner, the measurements are prone to be subjective. Herein, we aimed to evaluate the interexaminer reproducibility of the tear meniscus measurements with OCT.
MATERIALS AND METHODS: In this prospective cross-sectional study, both eyes of 300 consecutive patients with and without dry eye were studied. Following routine ophthalmologic examination, tear-film OCT images were obtained. Two examiners, who were unaware of the other examiner's results, measured the TMH (i.e. the line connecting the intersection of the meniscus with the cornea/sclera and eyelid) and cross-sectional TMA. The reliability and correlation of the two examiners' results were assessed.
RESULTS: Four right and six left eyes were excluded from the final analysis, so a total of 590 eyes were evaluated. The mean difference of the two examiners' measurements of both eyes was -0.001 ± 0.027 mm(2) in TMA, and -21.29 ± 39.95 μm in TMH. An agreement between the two examiners was found regarding TMA and TMH measurements for right and left, as well as both eyes (Cronbach's alpha > 0.900, for all). Also, the correlation between both variables was high (inter item correlation matrix > 0.840, for all).
CONCLUSIONS: We showed a strong statistical agreement for both TMA and TMH measurements. According to our results, we believe that FD-OCT device is dependable in measuring the TMA and TMH values, given that its results are reproducible.

Entities:  

Keywords:  Dry eye syndromes; optical coherence tomography; optical imaging; tear meniscus; tears

Mesh:

Year:  2014        PMID: 24749829     DOI: 10.3109/02713683.2014.898311

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN: 0271-3683            Impact factor:   2.424


  6 in total

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Authors:  Min Kyu Yang; Namju Kim; Ho-Kyung Choung; Sang In Khwarg
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-07-24       Impact factor: 3.117

Review 2.  The Growing Need for Validated Biomarkers and Endpoints for Dry Eye Clinical Research.

Authors:  Neeta S Roy; Yi Wei; Eric Kuklinski; Penny A Asbell
Journal:  Invest Ophthalmol Vis Sci       Date:  2017-05-01       Impact factor: 4.799

3.  Bony nasolacrimal duct size and outcomes of nasolacrimal silicone intubation for incomplete primary acquired nasolacrimal duct obstruction.

Authors:  Min Kyu Yang; Ho-Seok Sa; Namju Kim; Jeong Hun Kim; Hokyung Choung; Sang In Khwarg
Journal:  PLoS One       Date:  2022-03-28       Impact factor: 3.240

4.  Application of Keratograph and Fourier-Domain Optical Coherence Tomography in Measurements of Tear Meniscus Height.

Authors:  Minjie Chen; Anji Wei; Jianjiang Xu; Xingtao Zhou; Jiaxu Hong
Journal:  J Clin Med       Date:  2022-02-28       Impact factor: 4.241

Review 5.  A Review of Imaging Biomarkers of the Ocular Surface.

Authors:  William W Binotti; Betul Bayraktutar; M Cuneyt Ozmen; Stephanie M Cox; Pedram Hamrah
Journal:  Eye Contact Lens       Date:  2020-03       Impact factor: 3.152

6.  Correlation of Measures From the OCULUS Keratograph and Clinical Assessments of Dry Eye Disease in the Dry Eye Assessment and Management Study.

Authors:  John E Sutphin; Gui-Shuang Ying; Vatinee Y Bunya; Yinxi Yu; Meng C Lin; Kathleen McWilliams; Elizabeth Schmucker; Eric J Kuklinski; Penny A Asbell; Maureen G Maguire
Journal:  Cornea       Date:  2021-07-21       Impact factor: 3.152

  6 in total

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