Literature DB >> 24748207

Capturing large shape variations of liver using population-based statistical shape models.

Amir H Foruzan1,2, Yen-Wei Chen3, Masatoshi Hori4, Yoshinobu Sato5, Noriyuki Tomiyama4.   

Abstract

PURPOSE: Statistical shape models (SSMs) represent morphological variations of a specific object. When there are large shape variations, the shape parameters constitute a large space that may include incorrect parameters. The human liver is a non-rigid organ subject to large deformations due to external forces or body position changes during scanning procedures. We developed and tested a population-based model to represent the shape of liver.
METHODS: Upper abdominal CT-scan input images are represented by a conventional shape model. The shape parameters of individual livers extracted from the CT scans are employed to classify them into different populations. Corresponding to each population, an SSM model is built. The liver surface parameter space is divided into several subspaces which are more compact than the original space. The proposed model was tested using 29 CT-scan liver image data sets. The method was evaluated by model compactness, reconstruction error, generality and specificity measures.
RESULTS: The proposed model is implemented and tested using CT scans that included liver shapes with large shape variations. The method was compared with conventional and recently developed shape modeling methods. The accuracy of the proposed model was nearly twice that achieved with the conventional model. The proposed population-based model was more general compared with the conventional model. The mean reconstruction error of the proposed model was 0.029 mm while that of the conventional model was 0.052 mm.
CONCLUSION: A population-based model to represent the shape of liver was developed and tested with favorable results. Using this approach, the liver shapes from CT scans were modeled by a more compact, more general, and more accurate model.

Entities:  

Keywords:  Medical image analysis; Population-based shape model; Shape representation; Statistical shape model

Mesh:

Year:  2014        PMID: 24748207     DOI: 10.1007/s11548-014-1000-5

Source DB:  PubMed          Journal:  Int J Comput Assist Radiol Surg        ISSN: 1861-6410            Impact factor:   2.924


  11 in total

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Journal:  Med Image Anal       Date:  2009-05-27       Impact factor: 8.545

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Journal:  Comput Math Methods Med       Date:  2013-09-29       Impact factor: 2.238

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2.  Stereological quantification of microvessels using semiautomated evaluation of X-ray microtomography of hepatic vascular corrosion casts.

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