Literature DB >> 2474776

Hippocampal 5-HT synthesis and release in vivo is decreased by infusion of 8-OHDPAT into the nucleus raphe dorsalis.

P H Hutson1, G S Sarna, M T O'Connell, G Curzon.   

Abstract

Infusion of the serotonin-1A (5-HT1A) agonist, 8-hydroxy-2-di(n-propylamino)tetralin (8-OHDPAT) (0.5, 1.0 and 2.0 micrograms) into the dorsal raphe, decreased extracellular 5-HT as measured by dialysis in the ventral hippocampus and also decreased 5-HT synthesis in both the hippocampus and the rest of the brain as measured by 5-hydroxytryptophan (5-HTP) accumulation following decarboxylase inhibition by NSD 1015.

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Year:  1989        PMID： 2474776     DOI： 10.1016/0304-3940(89)90698-8

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  38 in total

1.  In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat.

Authors:  Laia Lladó-Pelfort; Marie-Bernadette Assié; Adrian Newman-Tancredi; Francesc Artigas; Pau Celada
Journal:  Psychopharmacology (Berl)       Date:  2011-12-03       Impact factor: 4.530

2.  Effect of 5-HT1A receptor agonists in two models of anxiety after dorsal raphe injection.

Authors:  G A Higgins; B J Jones; N R Oakley
Journal:  Psychopharmacology (Berl)       Date:  1992       Impact factor: 4.530

3.  Preferential in vivo action of F15599, a novel 5-HT(1A) receptor agonist, at postsynaptic 5-HT(1A) receptors.

Authors:  L Lladó-Pelfort; M-B Assié; A Newman-Tancredi; F Artigas; P Celada
Journal:  Br J Pharmacol       Date:  2010-08       Impact factor: 8.739

4.  Ex vivo inhibitory effect of the 5-HT uptake blocker citalopram on 5-HT synthesis.

Authors:  C Moret; M Briley
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

Review 5.  5-HT(1A) receptor function in major depressive disorder.

Authors:  Jonathan Savitz; Irwin Lucki; Wayne C Drevets
Journal:  Prog Neurobiol       Date:  2009-02-07       Impact factor: 11.685

6.  Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study.

Authors:  I Malagié; A C Trillat; E Douvier; M C Anmella; M C Dessalles; C Jacquot; A M Gardier
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1996-12       Impact factor: 3.000

7.  Serotonergic influences on male sexual behavior of rhesus monkeys: effects of serotonin agonists.

Authors:  S M Pomerantz; B C Hepner; J M Wertz
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

8.  Monoamine oxidase inhibitors increase preferentially extracellular 5-hydroxytryptamine in the midbrain raphe nuclei. A brain microdialysis study in the awake rat.

Authors:  P Celada; F Artigas
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-06       Impact factor: 3.000

9.  Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat.

Authors:  K Yoshimoto; W J McBride
Journal:  Neurochem Res       Date:  1992-05       Impact factor: 3.996

10.  Anxiogenic-like effect of infusing 1-(3-chlorophenyl) piperazine (mCPP) into the hippocampus.

Authors:  P Whitton; G Curzon
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530
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