Literature DB >> 2474760

Effect of 5-azacytidine on gene expression in marrow stromal cells.

D F Andrews1, J Nemunaitis, C Tompkins, J W Singer.   

Abstract

When exposed to 5-azacytidine, marrow stromal cells from active long-term marrow cultures and cell lines derived from simian virus 40-transformed stromal cells rapidly upregulated c-abl and interleukin-6 transcripts while downregulating the expression of collagen I, a major matrix protein. Similar effects occurred with interleukin-1 alpha and tumor necrosis factor alpha, although the time course was considerably prolonged.

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Year:  1989        PMID： 2474760      PMCID： PMC362350          DOI： 10.1128/mcb.9.6.2748-2751.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  36 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  Cloning and characterization of five overlapping cDNAs specific for the human pro alpha 1(I) collagen chain.

Authors:  M L Chu; J C Myers; M P Bernard; J F Ding; F Ramirez
Journal:  Nucleic Acids Res       Date:  1982-10-11       Impact factor: 16.971

3.  Inhibition of DNA methyltransferase and induction of Friend erythroleukemia cell differentiation by 5-azacytidine and 5-aza-2'-deoxycytidine.

Authors:  F Creusot; G Acs; J K Christman
Journal:  J Biol Chem       Date:  1982-02-25       Impact factor: 5.157

4.  Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes.

Authors:  D W Cleveland; M A Lopata; R J MacDonald; N J Cowan; W J Rutter; M W Kirschner
Journal:  Cell       Date:  1980-05       Impact factor: 41.582

5.  The organization of the human HPRT gene.

Authors:  S H Kim; J C Moores; D David; J G Respess; D J Jolly; T Friedmann
Journal:  Nucleic Acids Res       Date:  1986-04-11       Impact factor: 16.971

6.  Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.

Authors:  H Aviv; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

7.  Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine.

Authors:  S M Taylor; P A Jones
Journal:  J Cell Physiol       Date:  1982-05       Impact factor: 6.384

8.  Pattern of methylation of two genes coding for housekeeping functions.

Authors:  R Stein; N Sciaky-Gallili; A Razin; H Cedar
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

9.  Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle.

Authors:  A Dugaiczyk; J A Haron; E M Stone; O E Dennison; K N Rothblum; R J Schwartz
Journal:  Biochemistry       Date:  1983-03-29       Impact factor: 3.162

10.  Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.

Authors:  J Y Wang; D Baltimore
Journal:  Mol Cell Biol       Date:  1983-05       Impact factor: 4.272
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  5 in total

1.  A highly conserved intronic sequence is involved in transcriptional regulation of the alpha 1(I) collagen gene.

Authors:  D J Liska; J L Slack; P Bornstein
Journal:  Cell Regul       Date:  1990-05

2.  A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

Authors:  Joyce E Ohm; Kelly M McGarvey; Xiaobing Yu; Linzhao Cheng; Kornel E Schuebel; Leslie Cope; Helai P Mohammad; Wei Chen; Vincent C Daniel; Wayne Yu; David M Berman; Thomas Jenuwein; Kevin Pruitt; Saul J Sharkis; D Neil Watkins; James G Herman; Stephen B Baylin
Journal:  Nat Genet       Date:  2007-01-09       Impact factor: 38.330

3.  Recombinant tumor necrosis factor alpha and interleukin 1 alpha increase expression of c-abl protooncogene mRNA in cultured human marrow stromal cells.

Authors:  D F Andrews; J J Nemunaitis; J W Singer
Journal:  Proc Natl Acad Sci U S A       Date:  1989-09       Impact factor: 11.205

4.  Cytokine-dependent long-term culture of highly enriched precursors of hematopoietic progenitor cells from human bone marrow.

Authors:  J Brandt; E F Srour; K van Besien; R A Briddell; R Hoffman
Journal:  J Clin Invest       Date:  1990-09       Impact factor: 14.808

5.  Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty.

Authors:  Carlos A Toro; Hollis Wright; Carlos F Aylwin; Sergio R Ojeda; Alejandro Lomniczi
Journal:  Nat Commun       Date:  2018-01-04       Impact factor: 14.919
  5 in total

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