Literature DB >> 24747560

Thrombosis, platelets, microparticles and PAH: more than a clot.

Katie L Lannan1, Richard P Phipps2, R James White3.   

Abstract

Pulmonary arterial hypertension (PAH) is a progressive disease that involves pathological remodeling, vasoconstriction and thrombosis. Alterations in hemostasis, coagulation and platelet activation are consistently observed in PAH patients. Microparticles derived from platelets, inflammatory cells and the endothelium are an increasingly well-recognized signal in a variety of cardiovascular diseases, including PAH. This review will focus on the roles of coagulation, thrombosis, platelet activation and microparticles in the pathology and progression of PAH.
Copyright © 2014. Published by Elsevier Ltd.

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Year:  2014        PMID: 24747560      PMCID: PMC4386061          DOI: 10.1016/j.drudis.2014.04.001

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  75 in total

Review 1.  Platelet activation: assessment and quantification.

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Journal:  Eur Heart J       Date:  2001-09       Impact factor: 29.983

2.  CD40 engagement up-regulates cyclooxygenase-2 expression and prostaglandin E2 production in human lung fibroblasts.

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Journal:  J Immunol       Date:  1998-02-01       Impact factor: 5.422

Review 3.  Pathobiology of pulmonary hypertension. The role of platelets and thrombosis.

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Journal:  Clin Chest Med       Date:  2001-09       Impact factor: 2.878

4.  CD40 expression by human fibroblasts.

Authors:  K M Fries; G D Sempowski; A A Gaspari; T Blieden; R J Looney; R P Phipps
Journal:  Clin Immunol Immunopathol       Date:  1995-10

5.  Increased tyrosine phosphorylation of platelet proteins including pp125(FAK) suggests endogenous activation and aggregation in pulmonary hypertension.

Authors:  Nair Y Maeda; Sergio P Bydlowski; Antonio A Lopes
Journal:  Clin Appl Thromb Hemost       Date:  2005-10       Impact factor: 2.389

6.  New predictors of outcome in idiopathic pulmonary arterial hypertension.

Authors:  Steven M Kawut; Evelyn M Horn; Ketevan K Berekashvili; Robert P Garofano; Rochelle L Goldsmith; Allison C Widlitz; Erika B Rosenzweig; Diane Kerstein; Robyn J Barst
Journal:  Am J Cardiol       Date:  2005-01-15       Impact factor: 2.778

7.  Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension.

Authors:  Revathi Rajkumar; Kazuhisa Konishi; Thomas J Richards; David C Ishizawar; Andrew C Wiechert; Naftali Kaminski; Ferhaan Ahmad
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-01-15       Impact factor: 4.733

8.  Fibrin resistance to lysis in patients with pulmonary hypertension other than thromboembolic.

Authors:  Massimo Miniati; Claudia Fiorillo; Matteo Becatti; Simonetta Monti; Matteo Bottai; Carlo Marini; Elisa Grifoni; Bruno Formichi; Carolina Bauleo; Chiara Arcangeli; Daniela Poli; Paolo Antonio Nassi; Rosanna Abbate; Domenico Prisco
Journal:  Am J Respir Crit Care Med       Date:  2010-01-14       Impact factor: 21.405

Review 9.  On the origin of microparticles: From "platelet dust" to mediators of intercellular communication.

Authors:  Leslie A Hargett; Natalie N Bauer
Journal:  Pulm Circ       Date:  2013-04       Impact factor: 3.017

Review 10.  Mechanisms of disease: pulmonary arterial hypertension.

Authors:  Ralph T Schermuly; Hossein A Ghofrani; Martin R Wilkins; Friedrich Grimminger
Journal:  Nat Rev Cardiol       Date:  2011-06-21       Impact factor: 32.419

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  14 in total

1.  Maresin 1 induces a novel pro-resolving phenotype in human platelets.

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2.  A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling.

Authors:  Benjamin A T Rodriguez; Arunoday Bhan; Andrew Beswick; Peter C Elwood; Teemu J Niiranen; Veikko Salomaa; David-Alexandre Trégouët; Pierre-Emmanuel Morange; Mete Civelek; Yoav Ben-Shlomo; Thorsten Schlaeger; Ming-Huei Chen; Andrew D Johnson
Journal:  Am J Hum Genet       Date:  2020-07-09       Impact factor: 11.025

3.  The Sequence of the Evil: A Case Report of Idiopathic Noncirrhotic Portal Hypertension Associated With Littoral Cell Angioma of the Spleen, 4 Years After the Successful Treatment of a Colon Cancer.

Authors:  Konstantinou Fotis; Liakopoulou Christina; Provatas Ioannis; Konstantinou Angelos; Loverdos Dionysios; Kokkinakis Evangelos
Journal:  J Clin Exp Hepatol       Date:  2018-08-27

Review 4.  The Use of Risk Assessment Tools and Prognostic Scores in Managing Patients with Pulmonary Arterial Hypertension.

Authors:  Manreet Kanwar; Amresh Raina; Lisa Lohmueller; Jidapa Kraisangka; Raymond Benza
Journal:  Curr Hypertens Rep       Date:  2019-04-25       Impact factor: 5.369

5.  The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety (2017 Grover Conference Series).

Authors:  Jacob S Brenner; Raisa Yu Kiseleva; Patrick M Glassman; Hamideh Parhiz; Colin F Greineder; Elizabeth D Hood; Vladimir V Shuvaev; Vladimir R Muzykantov
Journal:  Pulm Circ       Date:  2017-12-20       Impact factor: 3.017

6.  Microparticles from β-thalassaemia/HbE patients induce endothelial cell dysfunction.

Authors:  Wasinee Kheansaard; Kunwadee Phongpao; Kittiphong Paiboonsukwong; Kovit Pattanapanyasat; Pornthip Chaichompoo; Saovaros Svasti
Journal:  Sci Rep       Date:  2018-08-29       Impact factor: 4.379

7.  The Evolution of Risk Assessment in Pulmonary Arterial Hypertension.

Authors:  Sandhya Murthy; Raymond Benza
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8.  Inducing mitophagy in diabetic platelets protects against severe oxidative stress.

Authors:  Seung Hee Lee; Jing Du; Jeremiah Stitham; Gourg Atteya; Suho Lee; Yaozu Xiang; Dandan Wang; Yu Jin; Kristen L Leslie; Geralyn Spollett; Anup Srivastava; Praveen Mannam; Allison Ostriker; Kathleen A Martin; Wai Ho Tang; John Hwa
Journal:  EMBO Mol Med       Date:  2016-07-01       Impact factor: 12.137

9.  The effect of nitric oxide inhalation on heart and pulmonary circulation in rabbits with acute massive pulmonary embolism.

Authors:  Zeming Zhang; Kun Pan; Lu Chen; Yancun Wang
Journal:  Exp Ther Med       Date:  2018-05-11       Impact factor: 2.447

10.  Long-Chain Non-Coding RNA Metastasis-Related Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes the Proliferation and Migration of Human Pulmonary Artery Smooth Muscle Cells (hPASMCs) by Regulating the MicroRNA-503 (miR-503)/Toll-Like Receptor 4 (TLR4) Signal Axis.

Authors:  Meng He; Juxin Shen; Chunyi Zhang; Yefeng Chen; Weisi Wang; Kelong Tao
Journal:  Med Sci Monit       Date:  2020-07-13
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