| Literature DB >> 2474629 |
P R Wood1, J Ripper, A J Radford, P G Bundesen, D B Rylatt, L E Cottis, M John, P Plackett.
Abstract
A series of monoclonal antibodies (MAbs), specific for Mycobacterium bovis and BCG strains, were tested extensively for cross-reactivity to a wide range of mycobacterial species using ELISA, Western blotting and dot-blot analysis. The MAbs bound specifically to M. bovis and BCG and showed limited cross-reactivity with some strains of M. tuberculosis. All these MAbs recognized a 22 kDa protein previously termed MPB70, and by competitive ELISA analysis appeared to detect at least three M. bovis-specific determinants on the MPB70 molecule.Entities:
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Year: 1988 PMID: 2474629 DOI: 10.1099/00221287-134-9-2599
Source DB: PubMed Journal: J Gen Microbiol ISSN: 0022-1287