Literature DB >> 24745475

Patterns of substance use among HIV-positive adults over 50: implications for treatment and medication adherence.

Jeffrey T Parsons1, Tyrel J Starks2, Brett M Millar3, Kailip Boonrai4, David Marcotte5.   

Abstract

BACKGROUND: The population of older adults living with HIV is increasing in the United States. Despite an increased focus on the health of HIV-positive older adults, knowledge about their substance use, a primary risk factor for HIV medication non-adherence, and the association between use, problems associated with use, and adherence behavior, is limited.
METHODS: Data were collected from 557 HIV-positive adults aged 50 and older in the New York City area via telephone interview. Participants reported the number of days in the past month on which they missed any doses of HIV medication as well as the number of days they used alcohol, marijuana, cocaine/crack, opiates, amyl nitrite (poppers), and other drugs. The severity of substance use associated problems was assessed using the DAST-10 and AUDIT-C.
RESULTS: The sample included gay/bisexual (40.4%) and heterosexual (28.1%) men as well as lesbian/bisexual (4.9%) and heterosexual (26.7%) women. Latent class analyses identified four distinct patterns of substance use: Exclusive Alcohol Use; Alcohol and Marijuana; Alcohol and Cocaine/Crack; and Multiple-Substance Use. Variability in the number of missed HIV medication days and perceptions of substance use associated problems were observed across classes, with poorest adherence reported in the Alcohol and Marijuana class, the Alcohol and Cocaine/Crack class, and the Multiple-Substance Use class. The latter two classes also reported the greatest perceived impairment from substance use.
CONCLUSIONS: Patterns of recent substance use were associated with varying levels of HIV medication adherence and perceived substance use impairment, indicating that substance type matters when considering the health of older adults living with HIV, and that multiple-substance use needs to be addressed by interventions aimed at improving medication adherence.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  HIV and aging; Medication adherence; Older adults; Substance use

Mesh:

Year:  2014        PMID: 24745475      PMCID: PMC4028151          DOI: 10.1016/j.drugalcdep.2014.02.704

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  46 in total

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2.  Using latent class analysis (LCA) to analyze patterns of drug use in a population of illegal opioid users.

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3.  Current sexual activity and risky sexual behavior in older men with or at risk for HIV infection.

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4.  The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test.

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  43 in total

1.  Cigarette Smoking and Antiretroviral Therapy (ART) Adherence in a Sample of Heavy Drinking HIV-Infected Men Who Have Sex with Men (MSM).

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Journal:  Drug Alcohol Depend       Date:  2017-07-08       Impact factor: 4.492

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Authors:  Katherine Quinn; Chris Sanders; Andrew E Petroll
Journal:  AIDS Educ Prev       Date:  2017-02

Review 4.  Substance Use Screening in HIV Care Settings: a Review and Critique of the Literature.

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5.  The Association Between Marijuana Use and HIV Continuum of Care Outcomes: a Systematic Review.

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Journal:  Curr HIV/AIDS Rep       Date:  2019-02       Impact factor: 5.071

6.  Establishing the feasibility, acceptability and preliminary efficacy of a multi-component behavioral intervention to reduce pain and substance use and improve physical performance in older persons living with HIV.

Authors:  Alison A Moore; Jordan E Lake; Suzette Glasner; Arun Karlamangla; Alexis Kuerbis; Diane Preciado; Jessica Jenkins; Blanca X Dominguez; Jury Candelario; Diana H Liao; Lingqi Tang; M Carrington Reid
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Review 7.  Review of recent behavioral interventions targeting older adults living with HIV/AIDS.

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8.  Association between alcohol consumption trajectories and clinical profiles among women and men living with HIV.

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10.  90-90-90-Plus: Maintaining Adherence to Antiretroviral Therapies.

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