Literature DB >> 24744662

Myeloma Cells with Auer Rod-like Inclusions.

Abbas Hashim Abdulsalam1, Fatin Mohammed Al-Yassin2.   

Abstract

Entities:  

Year:  2012        PMID: 24744662      PMCID: PMC3986969          DOI: 10.5505/tjh.2012.72324

Source DB:  PubMed          Journal:  Turk J Haematol        ISSN: 1300-7777            Impact factor:   1.831


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Myeloma cells with Auer-rod like inclusions Analysis of bone marrow aspirate obtained from a 47-year-old female that presented with backache showed that she had IgG-κ-type multiple myeloma and renal impairment. FBC showed the following: Hb: 100 g L–1; Hct: 0.34 l/l; WBC: 9.5 x 109 L–1; platelet count: 194 x 109 L–1; differential count: normal. The presented image showings heavily granulated myeloma cells, some with Auer rod-like inclusions. Auer rod-like inclusions in myeloma are composed of crystallized lysosomal enzyme depositions. They are distinguished from intracytoplasmic immunoglobulin crystals. The factors that predispose to Auer rod-like inclusions in myeloma are unknown; however, in all reported cases paraprotein was of the kappa type. [1]Written informed consent was obtained from the patient. Conflict of Interest Statement The authors of this paper have no conflicts of interest,including specific financial interests, relationships, and/or affiliations relevant to the subject matter or materials included.
  1 in total

Review 1.  Auer rod-like intracytoplasmic inclusions in multiple myeloma. A case report and review of the literature.

Authors:  G Hütter; D Nowak; I W Blau; E Thiel
Journal:  Int J Lab Hematol       Date:  2008-01-07       Impact factor: 2.877

  1 in total

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