Literature DB >> 24744166

The accuracy of a continuous volumetric balancing system in pediatric continuous renal replacement therapy.

Mark R Hanudel1, Isidro B Salusky, Joshua J Zaritsky.   

Abstract

BACKGROUND: In pediatric continuous renal replacement therapy (CRRT) patients, accurate ultrafiltration (UF) measurement is essential, as both over- and under-UF may result in suboptimal outcomes. Traditionally, CRRT has relied on scale-based UF measurements; however, the recent development of a continuous volumetric balancing system has allowed for the advent of scale-less CRRT.
METHODS: To assess the accuracy of the volumetric balancing system, we designed a continuously measuring digital scale, which accounted for dialysate use and collected effluent, allowing us to independently measure UF volume and compare it with the machine reported UF volume.
RESULTS: In four low weight (6.9-16.7 kg) pediatric CRRT patients, we measured the UF volume over 20 separate runs, comprising a total of 318 hours. Over this time, the total measured UF volume was 50,550 mL ± 296 mL, whereas the total reported UF volume was 50,733 mL, a difference of 183 mL ± 296 mL (0.6 ± 0.9 ml/h), or 0.4 ± 0.6%. For each patient, over 48-112 hours per patient, the differences between the total measured and total reported UF volumes ranged from -7.8 ± 1.7 ml/h to +9.7 ± 1.8 ml/h, or -6.0 ± 1.3% to +5.4 ± 1.0%.
CONCLUSIONS: In low-weight, pediatric CRRT patients, the scale-less continuous volumetric balancing system delivers accurate ultrafiltration.

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Year:  2014        PMID: 24744166      PMCID: PMC4339043          DOI: 10.5301/ijao.5000296

Source DB:  PubMed          Journal:  Int J Artif Organs        ISSN: 0391-3988            Impact factor:   1.595


  8 in total

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2.  Clinical course and mortality risk factors in critically ill children requiring continuous renal replacement therapy.

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Authors:  Stuart L Goldstein; Michael J G Somers; Michelle A Baum; Jordan M Symons; Patrick D Brophy; Douglas Blowey; Timothy E Bunchman; Cheryl Baker; Theresa Mottes; Nancy McAfee; Joni Barnett; Gloria Morrison; Kristine Rogers; James D Fortenberry
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5.  Effect of fluid overload and dose of replacement fluid on survival in hemofiltration.

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7.  Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry.

Authors:  Scott M Sutherland; Michael Zappitelli; Steven R Alexander; Annabelle N Chua; Patrick D Brophy; Timothy E Bunchman; Richard Hackbarth; Michael J G Somers; Michelle Baum; Jordan M Symons; Francisco X Flores; Mark Benfield; David Askenazi; Deepa Chand; James D Fortenberry; John D Mahan; Kevin McBryde; Douglas Blowey; Stuart L Goldstein
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8.  The NxStage System One.

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  8 in total
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1.  Pediatric continuous renal replacement therapy: have practice changes changed outcomes? A large single-center ten-year retrospective evaluation.

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  1 in total

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