| Literature DB >> 24743882 |
Shlomit Schaal1, Aleksandr Kagan1, Yujuan Wang2, Chi-Chao Chan2, Henry J Kaplan1.
Abstract
IMPORTANCE: Acute retinal necrosis (ARN) is an infectious retinitis primarily caused by the herpesviruses. Although the Epstein-Barr virus (EBV) has been implicated as a cause of ARN, to our knowledge, there has been no histopathologic documentation. We report the clinical history and histopathologic confirmation that EBV can cause ARN. OBSERVATIONS: Clinical course and histopathology of a patient diagnosed with ARN caused by infection with EBV confirmed by molecular pathology. CONCLUSIONS AND RELEVANCE: Epstein-Barr virus is a recognized cause of intraocular inflammation and has been implicated as a possible cause of ARN. However, to our knowledge, tissue demonstration of EBV in a patient with ARN has not previously been reported. We identified the organism in the necrotic retina of a patient receiving immunosuppression because of idiopathic pulmonary fibrosis.Entities:
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Year: 2014 PMID： 24743882 PMCID： PMC4143326 DOI： 10.1001/jamaophthalmol.2014.266
Source DB: PubMed Journal: JAMA Ophthalmol ISSN： 2168-6165 Impact factor: 7.389