Literature DB >> 24743789

A chemical approach to "rewire" neural progenitor cells.

Min-Zu Wu1, Mo Li1, Guang-Hui Liu2, Juan Carlos Izpisua Belmonte1.   

Abstract

Generation of neural progenitor cells (NPCs) from pluripotent stem cells including ESCs and iPSCs and derivation of NPCs from somatic tissues have been considered promising approaches that could be used therapeutically to restore function in patients suffering neurodegenerative diseases. A new study published in Cell Research shows, for the first time, the generation of NPCs from somatic cells by small molecule compounds under hypoxia without exogenous transcription factors.

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Year:  2014        PMID： 24743789      PMCID： PMC4042174          DOI： 10.1038/cr.2014.51

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  12 in total

1.  Direct conversion of fibroblasts into stably expandable neural stem cells.

Authors:  Marc Thier; Philipp Wörsdörfer; Yenal B Lakes; Raphaela Gorris; Stefan Herms; Thoralf Opitz; Dominic Seiferling; Tamara Quandel; Per Hoffmann; Markus M Nöthen; Oliver Brüstle; Frank Edenhofer
Journal:  Cell Stem Cell       Date:  2012-03-22       Impact factor: 24.633

2.  Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor.

Authors:  Karen L Ring; Leslie M Tong; Maureen E Balestra; Robyn Javier; Yaisa Andrews-Zwilling; Gang Li; David Walker; William R Zhang; Anatol C Kreitzer; Yadong Huang
Journal:  Cell Stem Cell       Date:  2012-06-07       Impact factor: 24.633

3.  A fresh look at iPS cells.

Authors:  Shinya Yamanaka
Journal:  Cell       Date:  2009-04-03       Impact factor: 41.582

4.  Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds.

Authors:  Pingping Hou; Yanqin Li; Xu Zhang; Chun Liu; Jingyang Guan; Honggang Li; Ting Zhao; Junqing Ye; Weifeng Yang; Kang Liu; Jian Ge; Jun Xu; Qiang Zhang; Yang Zhao; Hongkui Deng
Journal:  Science       Date:  2013-07-18       Impact factor: 47.728

Review 5.  Stem cells for the treatment of neurological disorders.

Authors:  Olle Lindvall; Zaal Kokaia
Journal:  Nature       Date:  2006-06-29       Impact factor: 49.962

Review 6.  Multipotent progenitor cells in the adult dentate gyrus.

Authors:  F H Gage; G Kempermann; T D Palmer; D A Peterson; J Ray
Journal:  J Neurobiol       Date:  1998-08

7.  Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc.

Authors:  Alessandra Giorgetti; Maria C N Marchetto; Mo Li; Diana Yu; Raffaella Fazzina; Yangling Mu; Antonio Adamo; Ida Paramonov; Julio Castaño Cardoso; Montserrat Barragan Monasterio; Cedric Bardy; Riccardo Cassiani-Ingoni; Guang-Hui Liu; Fred H Gage; Juan Carlos Izpisua Belmonte
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-18       Impact factor: 11.205

8.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

9.  A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog.

Authors:  Justin K Ichida; Joel Blanchard; Kelvin Lam; Esther Y Son; Julia E Chung; Dieter Egli; Kyle M Loh; Ava C Carter; Francesco P Di Giorgio; Kathryn Koszka; Danwei Huangfu; Hidenori Akutsu; David R Liu; Lee L Rubin; Kevin Eggan
Journal:  Cell Stem Cell       Date:  2009-10-08       Impact factor: 24.633

Review 10.  The role of oxygen availability in embryonic development and stem cell function.

Authors:  M Celeste Simon; Brian Keith
Journal:  Nat Rev Mol Cell Biol       Date:  2008-02-20       Impact factor: 94.444
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