| Literature DB >> 2474154 |
S M Gabriel1, L M Kaplan, J B Martin, J I Koenig.
Abstract
Galanin-like immunoreactivity (Gal-LI), as determined by radioimmunoassay, was detectable in the brain and gastrointestinal tract by day 15 of gestation. Concentrations of Gal-LI increased after birth in the hypothalamus but decreased in the stomach and duodenum. A sex difference in Gal-LI concentrations appeared during puberty in the median eminence, neurointermediate lobe, and the anterior pituitary (AP), where females had higher Gal-LI concentrations compared to males. This difference was most pronounced in the AP; adult females had up to 4-fold greater Gal-LI concentrations and 5-fold more abundant rGal-specific mRNA compared to males.Entities:
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Year: 1989 PMID: 2474154 DOI: 10.1016/0196-9781(89)90045-4
Source DB: PubMed Journal: Peptides ISSN: 0196-9781 Impact factor: 3.750