Literature DB >> 24740463

Successful platelet count recovery in lupus-associated thrombocytopenia with the thrombopoietin agonist eltrombopag.

Phillip Scheinberg1, Cristiane Carvalho Singulane, Luis Sergio Guedes Barbosa, Morton Scheinberg.   

Abstract

Eltrombopag is a new thrombomimetic medication approved for the treatment of immune thrombocytopenia. There are very few reports on the use of eltrombopag in patients with thrombocytopenia associated with sytemic lupus.We present a recent case of a patient with lupus with severe thrombocytopenia refractory to conventional therapy and full recovery with the use of eltrombopag. The present status of the literature with the use of this medication in patients with lupus is reviewed and discussed.

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Year:  2014        PMID： 24740463     DOI： 10.1007/s10067-014-2600-8

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  18 in total

1.  Tofacitinib in combination with nonbiologic disease-modifying antirheumatic drugs in patients with active rheumatoid arthritis: a randomized trial.

Authors:  Joel Kremer; Zhan-Guo Li; Stephen Hall; Roy Fleischmann; Mark Genovese; Emilio Martin-Mola; John D Isaacs; David Gruben; Gene Wallenstein; Sriram Krishnaswami; Samuel H Zwillich; Tamas Koncz; Richard Riese; John Bradley
Journal:  Ann Intern Med       Date:  2013-08-20       Impact factor: 25.391

2.  AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP.

Authors:  James B Bussel; David J Kuter; James N George; Robert McMillan; Louis M Aledort; George T Conklin; Alan E Lichtin; Roger M Lyons; Jorge Nieva; Jeffrey S Wasser; Israel Wiznitzer; Reggie Kelly; Chien-Feng Chen; Janet L Nichol
Journal:  N Engl J Med       Date:  2006-10-19       Impact factor: 91.245

3.  Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug.

Authors:  Ronan Desmond; Danielle M Townsley; Bogdan Dumitriu; Matthew J Olnes; Phillip Scheinberg; Margaret Bevans; Ankur R Parikh; Kinneret Broder; Katherine R Calvo; Colin O Wu; Neal S Young; Cynthia E Dunbar
Journal:  Blood       Date:  2013-12-17       Impact factor: 22.113

Review 4.  Recombinant human thrombopoietin: basic biology and evaluation of clinical studies.

Authors:  David J Kuter; C Glenn Begley
Journal:  Blood       Date:  2002-11-15       Impact factor: 22.113

5.  Thrombocytopenia caused by the development of antibodies to thrombopoietin.

Authors:  J Li; C Yang; Y Xia; A Bertino; J Glaspy; M Roberts; D J Kuter
Journal:  Blood       Date:  2001-12-01       Impact factor: 22.113

6.  Successful treatment of severe thrombocytopenia with romiplostim in a pregnant patient with systemic lupus erythematosus.

Authors:  J K Alkaabi; S Alkindi; N Al Riyami; F Zia; L M A Balla; S M Balla
Journal:  Lupus       Date:  2012-12       Impact factor: 2.911

7.  Romiplostim or standard of care in patients with immune thrombocytopenia.

Authors:  David J Kuter; Mathias Rummel; Ralph Boccia; B Gail Macik; Ingrid Pabinger; Dominik Selleslag; Francesco Rodeghiero; Beng H Chong; Xuena Wang; Dietmar P Berger
Journal:  N Engl J Med       Date:  2010-11-11       Impact factor: 91.245

Review 8.  Immune thrombocytopenia -- what are the new treatment options?

Authors:  Simon Hallam; Drew Provan; Adrian C Newland
Journal:  Expert Opin Biol Ther       Date:  2013-05-17       Impact factor: 4.388

9.  Eltrombopag for the treatment of chronic idiopathic thrombocytopenic purpura.

Authors:  James B Bussel; Gregory Cheng; Mansoor N Saleh; Bethan Psaila; Lidia Kovaleva; Balkis Meddeb; Janusz Kloczko; Habib Hassani; Bhabita Mayer; Nicole L Stone; Michael Arning; Drew Provan; Julian M Jenkins
Journal:  N Engl J Med       Date:  2007-11-29       Impact factor: 91.245

10.  Hematological disorders in patients with systemic lupus erythematosus.

Authors:  Fozya Bashal
Journal:  Open Rheumatol J       Date:  2013-10-18
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  4 in total

1.  Eltrombopag in Combination with Rabbit Anti-thymocyte Globulin/Cyclosporine A in Immunosuppressive Therapy-naïve Patients with Aplastic Anemia in Japan.

Authors:  Kazunori Imada; Naoshi Obara; Hiroatsu Iida; Kenji Imajo; Tetsuo Maeda; Kensuke Usuki; Zhang Fanghong; Yosuke Hombo; Takeshi Tajima; Akiko Kumagai; Akira Matsuda; Shinji Nakao
Journal:  Intern Med       Date:  2020-11-23       Impact factor: 1.271

Review 2.  Cryptic conspirators: a conversation about thrombocytopenia and antiphospholipid syndrome.

Authors:  Andrew P Vreede; Paula L Bockenstedt; W Joseph McCune; Jason S Knight
Journal:  Curr Opin Rheumatol       Date:  2019-05       Impact factor: 5.006

3.  Eltrombopag Improves Refractory Thrombocytopenia in a Patient with Systemic Lupus Erythematosus.

Authors:  Natsuki Shima; Keiichi Sumida; Masahiro Kawada; Akinari Sekine; Masayuki Yamanouchi; Rikako Hiramatsu; Noriko Hayami; Eiko Hasegawa; Tatsuya Suwabe; Junichi Hoshino; Naoki Sawa; Kenmei Takaichi; Kenichi Ohashi; Takeshi Fujii; Yoshifumi Ubara
Journal:  Case Rep Rheumatol       Date:  2018-08-15

Review 4.  Lupus thrombocytopenia: pathogenesis and therapeutic implications.

Authors:  Nikolaos Galanopoulos; Anna Christoforidou; Zoe Bezirgiannidou
Journal:  Mediterr J Rheumatol       Date:  2017-03-28
  4 in total

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