Literature DB >> 24740414

Retraction. Up-regulation of pVHL along with down-regulation of HIF-1α by NDRG2 expression attenuates proliferation and invasion in renal cancer cells.

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Abstract

Entities:  

Year:  2014        PMID: 24740414      PMCID: PMC3989322          DOI: 10.1371/journal.pone.0095904

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


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The authors retract this publication due to concerns about the cell lines employed in the study. One part of the study involves an assessment of the effects of NDRG2 on the expression of pVHL, HIF-1α and VEGF in 786-O cells. After the publication of the article, a reader raised concerns that the human renal cancer cell lines 786-O and A498 used in the study lack HIF-1α. In addition the cell line 786-O has been reported to be VHL negative. The authors have completed a short tandem repeat analysis on the cell lines and this has revealed cross-contamination, which compromises the relevance of the work to renal cell carcinoma, and thus the conclusions of the study. In the light of this, the authors retract this publication.
  1 in total

1.  Up-regulation of pVHL along with down-regulation of HIF-1α by NDRG2 expression attenuates proliferation and invasion in renal cancer cells.

Authors:  Lei Gao; Guo-jun Wu; Bei Liu; Ming-zhi Shen; Tie-jun Pan; Chui-gong Yu; Qin-hao Wang; Yi Ru; Xi-ping Liu; Tian-shui Niu; Guo-dong Wang; Ming Wei; Rui-xiao Li; Libo Yao; He Wang; Xia Li
Journal:  PLoS One       Date:  2013-12-20       Impact factor: 3.240

  1 in total
  2 in total

1.  Human biosample authentication using the high-throughput, cost-effective SNPtrace(TM) system.

Authors:  May M Y Liang-Chu; Mamie Yu; Peter M Haverty; Julie Koeman; Janet Ziegle; Marie Lee; Richard Bourgon; Richard M Neve
Journal:  PLoS One       Date:  2015-02-25       Impact factor: 3.240

2.  Human sample authentication in biomedical research: comparison of two platforms.

Authors:  Harshitha Shobha Manjunath; Nicola James; Rebecca Mathew; Muna Al Hashmi; Lee Silcock; Ida Biunno; Pasquale De Blasio; Chidambaram Manickam; Sara Tomei
Journal:  Sci Rep       Date:  2021-07-07       Impact factor: 4.379

  2 in total

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