Literature DB >> 2474039

Equine interferons following exposure to equid herpesvirus-1 or -4.

N Edington1, C G Bridges, L Griffiths.   

Abstract

When 23 ponies were infected with equid herpesvirus-1 or -4 (EHV-1 or EHV-4), nasal shedding of interferon (IFN) correlated closely with the duration of viral excretion. Equine interferon (EqIFN) was detected in the serum only from animals infected with the EHV-1 virus, and here high levels correlated with clinical symptoms of locomotor disorder and indicated a poor prognosis. Low levels of IFN were detected in explanted mononuclear cells from ponies infected with either virus.

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Year:  1989        PMID： 2474039     DOI： 10.1089/jir.1989.9.389

Source DB:  PubMed          Journal:  J Interferon Res        ISSN： 0197-8357


  6 in total

1.  Transforming growth factor-beta induced by live or ultraviolet-inactivated equid herpes virus type-1 mediates immunosuppression in the horse.

Authors:  S Charan; K Palmer; P Chester; A R Mire-Sluis; A Meager; N Edington
Journal:  Immunology       Date:  1997-04       Impact factor: 7.397

2.  Equid Herpesvirus 1 Targets the Sensitization and Induction Steps To Inhibit the Type I Interferon Response in Equine Endothelial Cells.

Authors:  Fatai S Oladunni; Sanjay Sarkar; Stephanie Reedy; Udeni B R Balasuriya; David W Horohov; Thomas M Chambers
Journal:  J Virol       Date:  2019-11-13       Impact factor: 5.103

3.  Equid herpesvirus 1 infection of endothelial cells requires activation of putative adhesion molecules: an in vitro model.

Authors:  D Smith; A Hamblin; N Edington
Journal:  Clin Exp Immunol       Date:  2002-08       Impact factor: 4.330

4.  Genomic analysis and mRNA expression of equine type I interferon genes.

Authors:  Olivier Detournay; David A Morrison; Bettina Wagner; Behdad Zarnegar; Eva Wattrang
Journal:  J Interferon Cytokine Res       Date:  2013-06-17       Impact factor: 2.607

5.  Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity.

Authors:  Christiane L Schnabel; Christine L Wimer; Gillian Perkins; Susanna Babasyan; Heather Freer; Christina Watts; Alicia Rollins; Nikolaus Osterrieder; Bettina Wagner
Journal:  BMC Vet Res       Date:  2018-08-22       Impact factor: 2.741

6.  Abortigenic but Not Neurotropic Equine Herpes Virus 1 Modulates the Interferon Antiviral Defense.

Authors:  Katrien C K Poelaert; Jolien Van Cleemput; Kathlyn Laval; Herman W Favoreel; Gisela Soboll Hussey; Roger K Maes; Hans J Nauwynck
Journal:  Front Cell Infect Microbiol       Date:  2018-09-12       Impact factor: 5.293
  6 in total

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