| Literature DB >> 2474033 |
T Hunziker1, C Boillat, H A Gerber, U Wiesmann, B U Wintroub.
Abstract
Using the Combi-ring-dish (CRD), a new culture device, organotypic cultures of human epidermal keratinocytes were grown on bovine eye lens capsules. In these highly differentiated cultures, typical suprabasal acantholysis was induced by pemphigus vulgaris antibodies. This in vitro pemphigus vulgaris model may be used to analyse keratinocyte-derived factors causing acantholysis in experimental pemphigus.Entities:
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Year: 1989 PMID： 2474033 DOI： 10.1111/1523-1747.ep12277586
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551