Literature DB >> 24739853

Testicular swelling: a rare manifestation of chronic lymphocytic leukemia presenting with Richter's syndrome.

Bhawna Jha1, Jasmita Dass, Ritesh Sachdev, Rahul Bhargava.   

Abstract

Richter syndrome (RS) represents the clinico-pathologic transformation of indolent lymphomas to an aggressive lymphoma, most commonly diffuse large B-cell lymphoma. Majority of the patients have a previous diagnosis of Chronic Lymphocytic Leukemia and the median time to transformation is 2-4 years. De novo RS is extremely uncommon. RS frequently arises in the lymph nodes or bone marrow and rarely presents with extra nodal involvement, common sites being the gastrointestinal tract, eye, central nervous system, lung and kidney. Involvement of testis by RS is extremely rare and we came across only one such reported case in the literature. We are reporting this case as our patient presented with de novo RS at an extremely uncommon extra nodal site, testis.

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Year:  2014        PMID: 24739853     DOI: 10.4103/0377-4929.130925

Source DB:  PubMed          Journal:  Indian J Pathol Microbiol        ISSN: 0377-4929            Impact factor:   0.740


  3 in total

1.  Rare case of Richter syndrome with testicular involvement successfully obtained good prognosis with rapid operation and immunochemotherapy.

Authors:  Kengo Kawase; Taku Naiki; Aya Naiki-Ito; Masamitsu Yanada; Yosuke Ikegami; Yuya Ota; Tatsuya Hattori; Nayuka Matsuyama; Takashi Hamakawa; Tetsuji Maruyama; Takahiro Yasui
Journal:  IJU Case Rep       Date:  2019-06-17

2.  Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling.

Authors:  Sean McPhillips; Randall Friese; Gary Vercruysse
Journal:  Int J Surg Case Rep       Date:  2014-10-23

3.  Chronic lymphocytic leukemia and concurrent seminoma in the same testis.

Authors:  Kosuke Miyai; Fumihisa Kumazawa; Kimiya Sato; Hitoshi Tsuda
Journal:  J Pathol Transl Med       Date:  2021-10-22
  3 in total

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