Literature DB >> 2473926

Voltage-activated and stretch-activated Ba2+ conducting channels in an osteoblast-like cell line (UMR 106).

R Duncan1, S Misler.   

Abstract

Calcium entry may mediate osteoblast activation by calciotropic hormones or changes in electrical fields or mechanical stress in bone. Using cell-attached patch clamping techniques, we have seen two Ba2+ conducting channels in UMR-106 osteoblast-like cells: (i) a voltage-dependent, dihydropyridine-sensitive channel resembling L-type Ca2+ channels in other cells, and (ii) a stretch-activated non-selective channel resembling those involved in mechanoreception and triggering of volume regulation in other cells.

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Year:  1989        PMID： 2473926     DOI： 10.1016/0014-5793(89)81420-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  30 in total

Review 1.  Mechanotransduction pathways in bone: calcium fluxes and the role of voltage-operated calcium channels.

Authors:  A J el Haj; L M Walker; M R Preston; S J Publicover
Journal:  Med Biol Eng Comput       Date:  1999-05       Impact factor: 2.602

2.  The effect of mechanical deformation on the distribution of potassium ions across the cell membrane of sutural cells.

Authors:  F McDonald; W J Houston
Journal:  Calcif Tissue Int       Date:  1992-06       Impact factor: 4.333

3.  Estimating the sensitivity of mechanosensitive ion channels to membrane strain and tension.

Authors:  Guillaume T Charras; Beatrice A Williams; Stephen M Sims; Mike A Horton
Journal:  Biophys J       Date:  2004-10       Impact factor: 4.033

4.  Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels and extracellular calcium, controls podosome assembly and bone resorption.

Authors:  A Miyauchi; K A Hruska; E M Greenfield; R Duncan; J Alvarez; R Barattolo; S Colucci; A Zambonin-Zallone; S L Teitelbaum; A Teti
Journal:  J Cell Biol       Date:  1990-12       Impact factor: 10.539

5.  Multiple forms of mechanosensitive ion channels in osteoblast-like cells.

Authors:  R M Davidson; D W Tatakis; A L Auerbach
Journal:  Pflugers Arch       Date:  1990-08       Impact factor: 3.657

Review 6.  Molecular force transduction by ion channels: diversity and unifying principles.

Authors:  Sergei Sukharev; Frederick Sachs
Journal:  J Cell Sci       Date:  2012-07-13       Impact factor: 5.285

7.  Caveolin-1 regulates P2X7 receptor signaling in osteoblasts.

Authors:  Vimal Gangadharan; Anja Nohe; Jeffrey Caplan; Kirk Czymmek; Randall L Duncan
Journal:  Am J Physiol Cell Physiol       Date:  2014-10-15       Impact factor: 4.249

8.  Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone.

Authors:  E L Barry; F A Gesek; S C Froehner; P A Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-11-21       Impact factor: 11.205

9.  Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.

Authors:  Dawei Liu; Damian C Genetos; Ying Shao; Derik J Geist; Jiliang Li; Hua Zhu Ke; Charles H Turner; Randall L Duncan
Journal:  Bone       Date:  2007-10-16       Impact factor: 4.398

10.  Cell swelling activates K+ and Cl- channels as well as nonselective, stretch-activated cation channels in Ehrlich ascites tumor cells.

Authors:  O Christensen; E K Hoffmann
Journal:  J Membr Biol       Date:  1992-07       Impact factor: 1.843
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