Increase in median power frequency of the myoelectric signal in pathological fatigue.

During bicycle ergometry, surface EMG analysis was performed on the m. vastus lateralis in a patient with pathological fatigue (due to skeletal muscle carnitine deficiency). With prolonged, submaximal, exercise (30% VO2 max, 2 h) the median frequency of the power density spectrum increased, despite fatigue and lactate production. This observation questions the general validity of the present concepts on myoelectric aspects of fatigue.