Literature DB >> 2473861

Hapten-specific cellular immune response producing glomerular injury.

T Oite1, F Shimizu, S Kagami, T Morioka.   

Abstract

A new model of experimental glomerulonephritis (GN) in which a cell-mediated (delayed-type) reaction predominated was established. Cationized TNP-BSA conjugates were planted in the kidney of rats by perfusion via the renal artery. Rats which had been sensitized with the TNP hapten 7 days previously revealed marked exudative and proliferative changes in their glomeruli, accompanied by transient proteinuria. A cellular influx was seen without deposition of any autologous antibody. The resulting data are compatible with the idea that cell-mediated immune reactions can participate in tissue damage in glomerular disease.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2473861      PMCID： PMC1541898     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  17 in total

1.  Active in situ immune complex glomerulonephritis using the hapten-carrier system: role of epitope density in cationic antigens.

Authors:  S Kagami; M Miyao; F Shimizu; T Oite
Journal:  Clin Exp Immunol       Date:  1988-10       Impact factor: 4.330

2.  Hapten-reactive helper lymphocytes.

Authors:  B Rubin; H Wigzell
Journal:  Nature       Date:  1973-04-13       Impact factor: 49.962

3.  A method of trace iodination of proteins for immunologic studies.

Authors:  P J McConahey; F J Dixon
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

4.  Studies on the genetic control of picryl chloride contact hypersensitivity reaction in inbred rats.

Authors:  K Nakamura; M Aizawa
Journal:  Transplant Proc       Date:  1981-06       Impact factor: 1.066

5.  Masugi nephritis in the nude mice and their normal littermates.

Authors:  K Okada; T Oite; I Kihara; T Morita; T Yamamoto
Journal:  Acta Pathol Jpn       Date:  1982-01

6.  Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli.

Authors:  D I Beller; J M Kiely; E R Unanue
Journal:  J Immunol       Date:  1980-03       Impact factor: 5.422

7.  Demonstration of a soluble mediator that induces exudates rich in Ia-positive macrophages.

Authors:  M G Scher; D I Beller; E R Unanue
Journal:  J Exp Med       Date:  1980-12-01       Impact factor: 14.307

8.  Quantitative studies of in situ immune complex glomerulonephritis in the rat induced by planted, cationized antigen.

Authors:  T Oite; S R Batsford; M J Mihatsch; H Takamiya; A Vogt
Journal:  J Exp Med       Date:  1982-02-01       Impact factor: 14.307

9.  Evidence for a pathogenic role of a cell-mediated immune mechanism in experimental glomerulonephritis.

Authors:  A K Bhan; E E Schneeberger; A B Collins; R T McCluskey
Journal:  J Exp Med       Date:  1978-07-01       Impact factor: 14.307

10.  A mononuclear cell component in experimental immunological glomerulonephritis.

Authors:  G F Schreiner; R S Cotran; V Pardo; E R Unanue
Journal:  J Exp Med       Date:  1978-02-01       Impact factor: 14.307
View more
  3 in total

1.  Nephrotoxic serum nephritis in nude rats: the roles of host immune reactions in the accelerated type.

Authors:  T Sato; H Kawachi; T Morioka; N Takashima; T Saeki; T Oite; N L Sato; M Takeuchi; F Shimizu
Journal:  Clin Exp Immunol       Date:  1993-01       Impact factor: 4.330

2.  Delayed-type hypersensitivity responses regulate collagen deposition in the lung.

Authors:  R Kimura; H Hu; J Stein-Streilein
Journal:  Immunology       Date:  1992-12       Impact factor: 7.397

3.  Selective planting of cationized, haptenized ovalbumin on the rat tubular basement membrane.

Authors:  K Joh; S Aizawa; K Ohkawa; T Morioka; T Oite; F Shimizu; S Batsford; A Vogt
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.