Literature DB >> 24737216

[Secondary telangiectatic osteosarcoma of the left femur. A case presentation of an unusual course of disease].

D Zajonz1, M Werner, S Panzert, A S Strübing, S Tiepolt, E Fabsits, P Brandmaier, C-E Heyde, T Prietzel.   

Abstract

BACKGROUND: This article presents the unusual case of a 73-year-old male patient who was treated with primary interlocking nailing after a pathological femoral fracture. DIAGNOSTICS: Despite comprehensive diagnostics including several biopsies, a tumor could not be detected. In 2008 when progressive cystic femoral destruction leading to loosening of the nail necessitated a partial femoral prosthesis, an osteosarcoma could first be diagnosed in the resected bone. THERAPY: Advanced progression of the tumor required an extended hip exarticulation. During the current restaging of the now 84-year-old patient no tumor could be detected.
CONCLUSION: When a malignancy cannot be excluded even by repeated biopsies of radiologically suspicious structures, an adequate tumor staging followed by close monitoring should be carried out. For a clinically silent, long-term course of cystic destruction of a long bone over several years, an age over 60 years and a lack of distant metastases, an atypical osteosarcoma should be considered in the differential diagnosis.

Entities:  

Mesh:

Year:  2014        PMID: 24737216     DOI: 10.1007/s00132-014-2311-5

Source DB:  PubMed          Journal:  Orthopade        ISSN: 0085-4530            Impact factor:   1.087


  8 in total

1.  Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols.

Authors:  Stefan S Bielack; Beate Kempf-Bielack; Günter Delling; G Ulrich Exner; Silke Flege; Knut Helmke; Rainer Kotz; Mechthild Salzer-Kuntschik; Matthias Werner; Winfried Winkelmann; Andreas Zoubek; Heribert Jürgens; Kurt Winkler
Journal:  J Clin Oncol       Date:  2002-02-01       Impact factor: 44.544

Review 2.  Pediatric and adult osteosarcoma: comparisons and contrasts in presentation and therapy.

Authors:  Robert S Benjamin; Shreyaskumar R Patel
Journal:  Cancer Treat Res       Date:  2009

3.  Five-year evolution of a telangiectatic osteosarcoma initially managed as an aneurysmal bone cyst.

Authors:  Tsuyoshi Saito; Yoshinao Oda; Ken-Ichi Kawaguchi; Kazuhiro Tanaka; Shuichi Matsuda; Akio Sakamoto; Yukihide Iwamoto; Masazumi Tsuneyoshi
Journal:  Skeletal Radiol       Date:  2005-05       Impact factor: 2.199

4.  Telangiectatic osteogenic sarcoma: a clinicopathologic study of 124 patients.

Authors:  A G Huvos; G Rosen; S S Bretsky; A Butler
Journal:  Cancer       Date:  1982-04-15       Impact factor: 6.860

Review 5.  The threat of misdiagnosis of primary osteosarcoma over the age of 60: a series of seven cases and review of the literature.

Authors:  Patrick Sadoghi; Andreas Leithner; Heimo Clar; Mathias Glehr; Christine Wibmer; Koppany Bodo; Franz Quehenberger; Reinhard Windhager
Journal:  Arch Orthop Trauma Surg       Date:  2009-11-28       Impact factor: 3.067

Review 6.  [Treatment concepts of benign bone tumors and tumor-like bone lesions].

Authors:  K-D Schaser; H J Bail; N P Haas; I Melcher
Journal:  Chirurg       Date:  2002-12       Impact factor: 0.955

7.  Prognostic factors in pulmonary metastasized high-grade osteosarcoma.

Authors:  Emilie P Buddingh; Jakob K Anninga; Michel I M Versteegh; Antonie H M Taminiau; R Maarten Egeler; Catherina S P van Rijswijk; Pancras C W Hogendoorn; Arjan C Lankester; Hans Gelderblom
Journal:  Pediatr Blood Cancer       Date:  2010-02       Impact factor: 3.167

8.  Osteosarcoma in the distal femur two years after an ipsilateral femoral shaft fracture: a case report.

Authors:  Oscar Dorrestijn; Paul C Jutte
Journal:  J Med Case Rep       Date:  2011-05-21
  8 in total

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