Literature DB >> 24735920

Next-generation genomic profiling of hepatocellular adenomas: a new era of individualized patient care.

Jens U Marquardt1, Snorri S Thorgeirsson2.   

Abstract

Hepatocellular adenomas (HCAs) are clinically relevant benign liver lesions that commonly occur in women on hormonal contraceptives. In this issue of Cancer Cell, Pilati and colleagues present an integrative multi-"omics"-based analysis of HCA and identify recurrent genetic alterations associated with adenoma-carcinoma transition and new drugable targets.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24735920      PMCID： PMC4078407          DOI： 10.1016/j.ccr.2014.03.032

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  10 in total

1.  Revisiting the pathology of resected benign hepatocellular nodules using new immunohistochemical markers.

Authors:  Paulette Bioulac-Sage; Gaelle Cubel; Charles Balabaud; Jessica Zucman-Rossi
Journal:  Semin Liver Dis       Date:  2011-02-22       Impact factor: 6.115

2.  Changing trends in malignant transformation of hepatocellular adenoma.

Authors:  Olivier Farges; Nelio Ferreira; Safi Dokmak; Jacques Belghiti; Pierre Bedossa; Valérie Paradis
Journal:  Gut       Date:  2011-01       Impact factor: 23.059

Review 3.  The epigenomics of cancer.

Authors:  Peter A Jones; Stephen B Baylin
Journal:  Cell       Date:  2007-02-23       Impact factor: 41.582

Review 4.  Cancer genome landscapes.

Authors:  Bert Vogelstein; Nickolas Papadopoulos; Victor E Velculescu; Shibin Zhou; Luis A Diaz; Kenneth W Kinzler
Journal:  Science       Date:  2013-03-29       Impact factor: 47.728

Review 5.  Hepatocellular benign tumors-from molecular classification to personalized clinical care.

Authors:  Jean-Charles Nault; Paulette Bioulac-Sage; Jessica Zucman-Rossi
Journal:  Gastroenterology       Date:  2013-02-26       Impact factor: 22.682

6.  Bi-allelic inactivation of TCF1 in hepatic adenomas.

Authors:  Olivier Bluteau; Emmanuelle Jeannot; Paulette Bioulac-Sage; Juan Martin Marqués; Jean-Frédéric Blanc; Hung Bui; Jean-Christophe Beaudoin; Dominique Franco; Charles Balabaud; Pierre Laurent-Puig; Jessica Zucman-Rossi
Journal:  Nat Genet       Date:  2002-09-23       Impact factor: 38.330

7.  Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours.

Authors:  Sandra Rebouissou; Mohamed Amessou; Gabrielle Couchy; Karine Poussin; Sandrine Imbeaud; Camilla Pilati; Tina Izard; Charles Balabaud; Paulette Bioulac-Sage; Jessica Zucman-Rossi
Journal:  Nature       Date:  2008-11-19       Impact factor: 49.962

8.  High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.

Authors:  Jean Charles Nault; Maxime Mallet; Camilla Pilati; Julien Calderaro; Paulette Bioulac-Sage; Christophe Laurent; Alexis Laurent; Daniel Cherqui; Charles Balabaud; Jessica Zucman-Rossi; Jessica Zucman Rossi
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

9.  Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas.

Authors:  Camilla Pilati; Mohamed Amessou; Michel P Bihl; Charles Balabaud; Jeanne Tran Van Nhieu; Valérie Paradis; Jean Charles Nault; Tina Izard; Paulette Bioulac-Sage; Gabrielle Couchy; Karine Poussin; Jessica Zucman-Rossi
Journal:  J Exp Med       Date:  2011-06-20       Impact factor: 14.307

10.  Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma.

Authors:  Zhengyan Kan; Hancheng Zheng; Xiao Liu; Shuyu Li; Thomas D Barber; Zhuolin Gong; Huan Gao; Ke Hao; Melinda D Willard; Jiangchun Xu; Robert Hauptschein; Paul A Rejto; Julio Fernandez; Guan Wang; Qinghui Zhang; Bo Wang; Ronghua Chen; Jian Wang; Nikki P Lee; Wei Zhou; Zhao Lin; Zhiyu Peng; Kang Yi; Shengpei Chen; Lin Li; Xiaomei Fan; Jie Yang; Rui Ye; Jia Ju; Kai Wang; Heather Estrella; Shibing Deng; Ping Wei; Ming Qiu; Isabella H Wulur; Jiangang Liu; Mariam E Ehsani; Chunsheng Zhang; Andrey Loboda; Wing Kin Sung; Amit Aggarwal; Ronnie T Poon; Sheung Tat Fan; Jun Wang; James Hardwick; Christoph Reinhard; Hongyue Dai; Yingrui Li; John M Luk; Mao Mao
Journal:  Genome Res       Date:  2013-06-20       Impact factor: 9.043
  10 in total
  3 in total

Review 1.  Functional and genetic deconstruction of the cellular origin in liver cancer.

Authors:  Jens U Marquardt; Jesper B Andersen; Snorri S Thorgeirsson
Journal:  Nat Rev Cancer       Date:  2015-11       Impact factor: 60.716

2.  Liver cancer oncogenomics: opportunities and dilemmas for clinical applications.

Authors:  Jens U Marquardt; Jesper B Andersen
Journal:  Hepat Oncol       Date:  2015

Review 3.  Current Proceedings in the Molecular Dissection of Hepatocellular Adenomas: Review and Hands-on Guide for Diagnosis.

Authors:  Diane Goltz; Hans-Peter Fischer
Journal:  Int J Mol Sci       Date:  2015-09-02       Impact factor: 5.923
  3 in total

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