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Literature DB >> 24735874

Ovol proteins: guardians against EMT during epithelial differentiation.

Abstract

Epithelial differentiation requires a balancing act to commit to epithelial fate while inhibiting both progenitor and mesenchymal traits. In this issue of Developmental Cell, Lee et al. (2014) and Watanabe et al. (2014) uncover a critical role of Ovol proteins in safeguarding this intricate process.

Entities: Disease Gene Species

Mesh：

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Year: 2014 PMID： 24735874 PMCID： PMC4106710 DOI： 10.1016/j.devcel.2014.04.002

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

10 in total

Review 1. The skinny on Slug.

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Journal: Mol Carcinog Date: 2010-10 Impact factor: 4.784

Review 2. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis.

Authors: Jing Yang; Robert A Weinberg
Journal: Dev Cell Date: 2008-06 Impact factor: 12.270

3. Slug and Sox9 cooperatively determine the mammary stem cell state.

Authors: Wenjun Guo; Zuzana Keckesova; Joana Liu Donaher; Tsukasa Shibue; Verena Tischler; Ferenc Reinhardt; Shalev Itzkovitz; Aurelia Noske; Ursina Zürrer-Härdi; George Bell; Wai Leong Tam; Sendurai A Mani; Alexander van Oudenaarden; Robert A Weinberg
Journal: Cell Date: 2012-03-02 Impact factor: 41.582

4. Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling.

Authors: Rumela Chakrabarti; Yong Wei; Rose-Anne Romano; Christina DeCoste; Yibin Kang; Satrajit Sinha
Journal: Stem Cells Date: 2012-07 Impact factor: 6.277

5. The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice.

Authors: X Dai; C Schonbaum; L Degenstein; W Bai; A Mahowald; E Fuchs
Journal: Genes Dev Date: 1998-11-01 Impact factor: 11.361

6. Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity.

Authors: Drazen Šošić; James A Richardson; Kai Yu; David M Ornitz; Eric N Olson
Journal: Cell Date: 2003-01-24 Impact factor: 41.582

7. Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.

Authors: Briana Lee; Alvaro Villarreal-Ponce; Magid Fallahi; Jeremy Ovadia; Peng Sun; Qian-Chun Yu; Seiji Ito; Satrajit Sinha; Qing Nie; Xing Dai
Journal: Dev Cell Date: 2014-04-14 Impact factor: 12.270

8. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis.

Authors: Colin Jamora; Pedro Lee; Pawel Kocieniewski; Mohamad Azhar; Ryoichi Hosokawa; Yang Chai; Elaine Fuchs
Journal: PLoS Biol Date: 2004-12-28 Impact factor: 8.029

9. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2.

Authors: Rumela Chakrabarti; Julie Hwang; Mario Andres Blanco; Yong Wei; Martin Lukačišin; Rose-Anne Romano; Kirsten Smalley; Song Liu; Qifeng Yang; Toni Ibrahim; Laura Mercatali; Dino Amadori; Bruce G Haffty; Satrajit Sinha; Yibin Kang
Journal: Nat Cell Biol Date: 2012-10-21 Impact factor: 28.824

Review 10. Epithelial-mesenchymal plasticity in carcinoma metastasis.

Authors: Jeff H Tsai; Jing Yang
Journal: Genes Dev Date: 2013-10-15 Impact factor: 11.361

10 in total

11 in total

1. Potential role of the OVOL1-OVOL2 axis and c-Myc in the progression of cutaneous squamous cell carcinoma.

Authors: Takamichi Ito; Gaku Tsuji; Fumitaka Ohno; Takeshi Nakahara; Hiroshi Uchi; Masutaka Furue
Journal: Mod Pathol Date: 2017-03-24 Impact factor: 7.842

2. SIGNET: single-cell RNA-seq-based gene regulatory network prediction using multiple-layer perceptron bagging.

Authors: Qinhuan Luo; Yongzhen Yu; Xun Lan
Journal: Brief Bioinform Date: 2022-01-17 Impact factor: 11.622

3. OVOL guides the epithelial-hybrid-mesenchymal transition.

Authors: Dongya Jia; Mohit Kumar Jolly; Marcelo Boareto; Princy Parsana; Steven M Mooney; Kenneth J Pienta; Herbert Levine; Eshel Ben-Jacob
Journal: Oncotarget Date: 2015-06-20

4. Coupling the modules of EMT and stemness: A tunable 'stemness window' model.

Authors: Mohit Kumar Jolly; Dongya Jia; Marcelo Boareto; Sendurai A Mani; Kenneth J Pienta; Eshel Ben-Jacob; Herbert Levine
Journal: Oncotarget Date: 2015-09-22

5. Expression of Ovol2 is related to epithelial characteristics and shows a favorable clinical outcome in hepatocellular carcinoma.

Authors: Hui Fu; Lisha Qi; Lu Chen; Yuchao He; Ning Zhang; Hua Guo
Journal: Onco Targets Ther Date: 2016-09-29 Impact factor: 4.147

6. Distinguishing mechanisms underlying EMT tristability.

Authors: Dongya Jia; Mohit Kumar Jolly; Satyendra C Tripathi; Petra Den Hollander; Bin Huang; Mingyang Lu; Muge Celiktas; Esmeralda Ramirez-Peña; Eshel Ben-Jacob; José N Onuchic; Samir M Hanash; Sendurai A Mani; Herbert Levine
Journal: Cancer Converg Date: 2017-11-01

7. Shavenbaby and Yorkie mediate Hippo signaling to protect adult stem cells from apoptosis.

Authors: Jérôme Bohère; Alexandra Mancheno-Ferris; Sandy Al Hayek; Jennifer Zanet; Philippe Valenti; Kohsuke Akino; Yuya Yamabe; Sachi Inagaki; Hélène Chanut-Delalande; Serge Plaza; Yuji Kageyama; Dani Osman; Cédric Polesello; François Payre
Journal: Nat Commun Date: 2018-11-30 Impact factor: 14.919