| Literature DB >> 24735475 |
Pham Van Khang1, Zhong-Guo Zhang, Yu-Hui Meng, De-An Guo, Xuan Liu, Li-Hong Hu, Lei Ma.
Abstract
Three new cardenolides (1-3) were isolated from the 90% ethanolic extract of the bark of a wild-type Calotropis gigantea. Their structures were determined by using NMR spectra and LC-MS analysis. Their inhibitory activities were evaluated against non-small cell lung carcinoma (A549) and human cervix epithelial adenocarcinoma (HeLa) cell lines. Compounds 1 and 3 exhibited strong inhibitory effect on two cancer cell lines.Entities:
Keywords: A459; Asclepiadaceae; Calotropis gigantea; HeLa; cardenolide
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Year: 2014 PMID： 24735475 DOI： 10.1080/14786419.2014.909419
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861