| Literature DB >> 24735070 |
Dimitris Limnios1, Christoforos G Kokotos.
Abstract
A cheap, mild, fast, and environmentally friendly oxidation of olefins to the corresponding epoxides is reported using polyfluoroalkyl ketones as efficient organocatalysts. Namely, 2,2,2-trifluoroacetophenone was identified as an improved organocatalyst for the epoxidation of alkenes. Various olefins, mono-, di-, and trisubstituted, are epoxidized chemoselectively in high to quantitative yields utilizing 2-5 mol % catalyst loading and H2O2 as the green oxidant.Entities:
Year: 2014 PMID： 24735070 DOI： 10.1021/jo5003938
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354