Literature DB >> 24733447

Screening for deep vein thrombosis after periacetabular osteotomy in adult patients: is it necessary?

Gregory G Polkowski1, Stephen T Duncan, Adam D Bloemke, Perry L Schoenecker, John C Clohisy.   

Abstract

BACKGROUND: The periacetabular osteotomy has become a common procedure for treating symptomatic acetabular dysplasia. Like other major hip procedures, there is concern regarding the risk of associated venous thromboembolic disease. Nevertheless, there is limited information regarding the need for screening, and optimal prophylactic measures have not been established. QUESTIONS/PURPOSES: We sought to determine the frequency of thromboembolic events (deep vein thrombosis [DVT] and symptomatic pulmonary embolism [PE]) associated with the periacetabular osteotomy in in patients receiving aspirin and mechanical compression prophylaxis.
METHODS: We performed a retrospective review of 134 adult patients (149 hips) treated with the periacetabular osteotomy during an 8-year period. During this period, 136 (91%) of the hips treated with a periacetabular osteotomy were screened within 1 week for DVT, whereas 13 (9%) could not be evaluated for various reasons. The mean age of the patients at the time of surgery was 30 years (range, 18-60 years), and no patients were lost to followup during the 4 to 6 months after surgery. The same thromboembolic prophylactic regimen was used for all patients. This consisted of 325 mg aspirin twice a day and compression stockings for 6 weeks and lower extremity pneumatic compression devices while hospitalized. Screening bilateral lower extremity ultrasonography was performed within 1 week (mean, 4 days) of the procedure to detect asymptomatic DVTs.
RESULTS: Of the 134 patients, two patients (two hips) with negative postoperative screening ultrasounds presented at 14 and 38 days postoperatively with clinical symptoms of DVT. Repeat ultrasound confirmed this diagnosis in both cases. There were no symptoms of PE. Screening venous ultrasonography did not identify any DVTs during the early postoperative period before discharge. These two patients were treated with 3 to 6 months of warfarin anticoagulation. Neither patient had persistent symptoms related to the DVT.
CONCLUSIONS: These data indicate that the risk of symptomatic DVT associated with periacetabular osteotomy is low (1%) with use of aspirin and mechanical compression prophylaxis. Furthermore, routine postoperative screening did not detect any patients with an asymptomatic DVT. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.

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Year:  2014        PMID: 24733447      PMCID: PMC4079874          DOI: 10.1007/s11999-014-3614-x

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  43 in total

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Authors:  Joshua J Jacobs; Michael A Mont; Kevin John Bozic; Craig J Della Valle; Stuart Barry Goodman; Courtland G Lewis; Adolph Chick J Yates; Lisa N Boggio; William C Watters; Charles M Turkelson; Janet L Wies; Patrick Sluka; Kristin Hitchcock
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3.  Early results of the Bernese periacetabular osteotomy: the learning curve at an academic medical center.

Authors:  Christopher L Peters; Jill A Erickson; Jerod L Hines
Journal:  J Bone Joint Surg Am       Date:  2006-09       Impact factor: 5.284

4.  Hospital-associated venous thromboembolism in children: incidence and clinical characteristics.

Authors:  Clifford M Takemoto; Sajeet Sohi; Kruti Desai; Raman Bharaj; Anuj Khanna; Susan McFarland; Sybil Klaus; Alia Irshad; Neil A Goldenberg; John J Strouse; Michael B Streiff
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5.  The value of ultrasound screening for proximal vein thrombosis after total hip arthroplasty--a prospective cohort study.

Authors:  F Verlato; O Bruchi; P Prandoni; G Camporese; G Maso; F Busonera; A Girolami; G M Andreozzi
Journal:  Thromb Haemost       Date:  2001-08       Impact factor: 5.249

Review 6.  Deep vein thrombosis prophylaxis: a comprehensive approach for total hip and total knee arthroplasty patient populations.

Authors:  A Miric; P Lombardi; T P Sculco
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7.  Incidence of deep vein thrombosis and pulmonary embolus following periacetabular osteotomy.

Authors:  Ira Zaltz; Paul Beaulé; John Clohisy; Perry Schoenecker; Daniel Sucato; David Podeszwa; Rafael Sierra; Robert Trousdale; Young-Jo Kim; Michael B Millis
Journal:  J Bone Joint Surg Am       Date:  2011-05       Impact factor: 5.284

8.  Complications associated with the Bernese periacetabular osteotomy for hip dysplasia in adolescents.

Authors:  Dinesh Thawrani; Daniel J Sucato; David A Podeszwa; Adriana DeLaRocha
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9.  Intermediate to long-term results following the Bernese periacetabular osteotomy and predictors of clinical outcome.

Authors:  Travis Matheney; Young-Jo Kim; David Zurakowski; Catherine Matero; Michael Millis
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10.  Medium-term outcome of periacetabular osteotomy and predictors of conversion to total hip replacement.

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Journal:  J Bone Joint Surg Am       Date:  2009-09       Impact factor: 5.284

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2.  Incidence of deep venous thrombosis following periacetabular and derotational femoral osteotomy: a case for mechanical prophylaxis.

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Journal:  J Hip Preserv Surg       Date:  2018-03-05

3.  Aspirin provides adequate VTE prophylaxis for patients undergoing hip preservation surgery, including periacetabular osteotomy.

Authors:  Ibrahim Azboy; Michael M Kheir; Ronald Huang; Javad Parvizi
Journal:  J Hip Preserv Surg       Date:  2018-04-05

Review 4.  Venous thromboembolism prophylaxis after hip preservation surgery: a review and presentation of institutional experience.

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5.  Incidences of deep vein thrombosis and major bleeding under the administration of fondaparinux for thromboprophylaxis after periacetabular osteotomy: a retrospective observational study.

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Journal:  J Hip Preserv Surg       Date:  2021-08-17

Review 6.  The efficacy and safety of anti-fibrinolytic agents in blood management following peri-acetabular osteotomy: A meta-analysis.

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Journal:  Medicine (Baltimore)       Date:  2018-08       Impact factor: 1.817

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