Literature DB >> 2473318

Anti-inflammatory effects of endothelin-1.

C L Chander1, A R Moore, F M Desa, D W Howat, D A Willoughby.   

Abstract

Endothelin-1 (ET-1), when injected intradermally in rats concurrently with FMLP, did not suppress cell accumulation 6 h later. In view of the fact that ET-1 can antagonize mediators of increased vascular permeability, it is proposed that this is further evidence that fluid and cell accumulation at an inflammatory site are separate processes.

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Year:  1989        PMID: 2473318     DOI: 10.1097/00005344-198900135-00064

Source DB:  PubMed          Journal:  J Cardiovasc Pharmacol        ISSN: 0160-2446            Impact factor:   3.105


  6 in total

1.  Professor Derek Albert Willoughby (1930-2004).

Authors:  K D Rainsford
Journal:  Inflammopharmacology       Date:  2005       Impact factor: 4.473

2.  Effects of endothelin-1 on vascular permeability in the conscious rat: interactions with platelet-activating factor.

Authors:  J G Filep; M G Sirois; A Rousseau; A Fournier; P Sirois
Journal:  Br J Pharmacol       Date:  1991-12       Impact factor: 8.739

3.  The involvement of endothelial dysfunction, nitric oxide and prostanoids in the rat gastric microcirculatory responses to endothelin-1.

Authors:  J Lopez-Belmonte; B J Whittle
Journal:  Br J Pharmacol       Date:  1994-05       Impact factor: 8.739

4.  Enhancement by endothelin-1 of microvascular permeability via the activation of ETA receptors.

Authors:  J G Filep; M G Sirois; E Földes-Filep; A Rousseau; G E Plante; A Fournier; M Yano; P Sirois
Journal:  Br J Pharmacol       Date:  1993-07       Impact factor: 8.739

5.  Effects of endothelin receptor antagonists on bradykinin-induced increases in macromolecular efflux.

Authors:  W G Mayhan; I Rubinstein
Journal:  Inflammation       Date:  1994-12       Impact factor: 4.092

6.  Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.

Authors:  J R Vane; J A Mitchell; I Appleton; A Tomlinson; D Bishop-Bailey; J Croxtall; D A Willoughby
Journal:  Proc Natl Acad Sci U S A       Date:  1994-03-15       Impact factor: 11.205

  6 in total

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