Literature DB >> 24732124

Clinical evaluation comparing the efficacy of aquacel Ag with vaseline gauze versus 1% silver sulfadiazine cream in toxic epidermal necrolysis.

Shu-Hung Huang1, Cen-Hung Lin, Kao-Ping Chang, Sheng-Hua Wu, Sin-Daw Lin, Chung-Sheng Lai, Su-Fei Ou, Su-Shin Lee.   

Abstract

OBJECTIVE: The purpose of this study was to determine whether using Aquacel Ag (ConvaTec, Skillman, New Jersey) with Vaseline (Unilever, London, England) gauze instead of silver sulfadiazine cream (SSD) as the wound care protocol to treat toxic epidermal necrolysis (TEN) can improve wound healing, pain control, and reduction of labor costs.
DESIGN: A retrospective chart review.
SETTING: A burn center with 2 plastic surgeons and 11 nursing staff. PATIENTS: A pathologist diagnosed TEN in 35 patients admitted to the burn center from 1995 to 2009. MAIN OUTCOME MEASURES: Parameters included the patient's profile, dressing choice, severity-of-illness score for TEN, time to 95% re-epithelialization, visual analog scale pain scores before second dressing change, and labor cost. The exclusion criterion was wound care with neither Aquacel Ag with Vaseline nor SSD exclusively.
RESULTS: Twenty patients were enrolled in this study. In the group using Aquacel Ag with Vaseline gauze, the visual analog scale score was significantly less than that of the SSD group (P = .02). Labor costs were significantly lower in the Aquacel Ag with Vaseline gauze group (P < .01). Commencement of specific dressing to 95% re-epithelialization (P = .09) and time spent in the second dressing change (P = .05) had no statistical significance between the 2 groups.
CONCLUSIONS: This study showed that Aquacel Ag with Vaseline gauze decreased pain and labor costs but did not shorten wound healing time. Thus, Aquacel Ag with Vaseline gauze can be an efficient method for treating TEN wounds.

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Year:  2014        PMID: 24732124     DOI: 10.1097/01.ASW.0000445919.06416.32

Source DB:  PubMed          Journal:  Adv Skin Wound Care        ISSN: 1527-7941            Impact factor:   2.347


  5 in total

1.  Development of a Chitosan-Vaseline Gauze Dressing with Wound-Healing Properties in Murine Models.

Authors:  Qing-Qing Fang; Xiao-Feng Wang; Wan-Yi Zhao; Bang-Hui Shi; Dong Lou; Chun-Ye Chen; Min-Xia Zhang; Xiaozhi Wang; Lie Ma; Wei-Qiang Tan
Journal:  Am J Trop Med Hyg       Date:  2020-02       Impact factor: 2.345

2.  Silver absorption in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis treated with silver-impregnated dressings. A case series.

Authors:  Hyunji Choi; Brianna Castillo; Lucia Seminario-Vidal
Journal:  Int Wound J       Date:  2018-06-11       Impact factor: 3.315

3.  Efficacy and Safety of 3 Nasal Packing Materials Used After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: A Comparative Study in China.

Authors:  Xi-Ling Zheng; Yu-Xiang Zhao; Min Xu
Journal:  Med Sci Monit       Date:  2017-04-25

4.  The Wound Healing Effect of Callicarpa nudiflora in Scalded Rats.

Authors:  Xu-Guang Zhang; Xiu-Min Li; Xin-Xin Zhou; Yong Wang; Wei-Yong Lai; Ying Liu; Yu-Chao Luo; Jun-Qing Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2019-05-02       Impact factor: 2.629

5.  Wound Healing and Antioxidant Properties of 80% Methanol Leaf Extract of Verbascum sinaiticum (Scrophulariaceae): An Ethiopian Medicinal Plant.

Authors:  Kalkidan Lulseged; Muluemebet Zinabu Akele; Alfoalem Araba Abiye; Besufekad Abebe; Solomon Assefa Huluka
Journal:  Evid Based Complement Alternat Med       Date:  2022-09-08       Impact factor: 2.650

  5 in total

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