Farzaneh Soltanipour1, Masoumeh Delaram2, Simin Taavoni3, Hamid Haghani3. 1. Alborz University of Medical Sciences, Karaj, Iran. 2. Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: swt_f@yahoo.com. 3. Tehran University of Medical Sciences, Tehran, Iran.
Abstract
OBJECTIVE: To compare the clinical efficacy of olive oil and the Saj(®) cream on the occurrence and severity of striae gravidarum. DESIGN: Parallel randomized controlled clinical trial. SETTING: West Health Centre, Lolagar and Akbarabadi Hospitals, Tehran, Iran. INTERVENTIONS:360 Nulliparous women at their second trimester of pregnancy randomly (simple randomization) allocated into three groups of olive oil, the Saj(®) cream, and control that finally 150 of them (50 subjects in each group) completed the study. Control group did not receive any medication/intervention. At gestational age of 38-40 weeks the participants were evaluated regarding the occurrence of striae on abdominal skin and its severity that were primary outcome of the study. RESULTS: In the olive oil group, striae occurred in 72% of the participants, which were mild, moderate, and severe in 32%, 26%, and 6% of the cases, respectively. In those who received Saj(®) cream, striae occurred in 64% of the cases, which were mild, moderate and severe in 16%, 34%, and 14% of the cases, respectively. With regard to the control group, striae occurred in 60% of the participants, among which striae were mild, moderate, and severe in 22%, 24%, and 14% of the cases, respectively. There were no statistically significant differences among the three studied groups regarding the incidence or severity of striae. CONCLUSION: Neither olive oil nor the Saj(®) cream were effective in preventing the occurrence of striae gravidarum or affecting its severity. Further studies to examine the effect of other herbal/chemical preparations on occurrence of striae gravidarum are recommended.
RCT Entities:
OBJECTIVE: To compare the clinical efficacy of olive oil and the Saj(®) cream on the occurrence and severity of striae gravidarum. DESIGN: Parallel randomized controlled clinical trial. SETTING: West Health Centre, Lolagar and Akbarabadi Hospitals, Tehran, Iran. INTERVENTIONS: 360 Nulliparous women at their second trimester of pregnancy randomly (simple randomization) allocated into three groups of olive oil, the Saj(®) cream, and control that finally 150 of them (50 subjects in each group) completed the study. Control group did not receive any medication/intervention. At gestational age of 38-40 weeks the participants were evaluated regarding the occurrence of striae on abdominal skin and its severity that were primary outcome of the study. RESULTS: In the olive oil group, striae occurred in 72% of the participants, which were mild, moderate, and severe in 32%, 26%, and 6% of the cases, respectively. In those who received Saj(®) cream, striae occurred in 64% of the cases, which were mild, moderate and severe in 16%, 34%, and 14% of the cases, respectively. With regard to the control group, striae occurred in 60% of the participants, among which striae were mild, moderate, and severe in 22%, 24%, and 14% of the cases, respectively. There were no statistically significant differences among the three studied groups regarding the incidence or severity of striae. CONCLUSION: Neither olive oil nor the Saj(®) cream were effective in preventing the occurrence of striae gravidarum or affecting its severity. Further studies to examine the effect of other herbal/chemical preparations on occurrence of striae gravidarum are recommended.