Xiaojuan Guo1, Huibo Zhang2, Min Liu1, Li Wang1, Tao Jiang1, Renyou Zhai1. 1. Department of Radiology, Beijing Chaoyang Hospital Affiliated to Capital University of Medical Sciences, Beijing 100020, China. 2. Department of Radiology, Beijing Chaoyang Hospital Affiliated to Capital University of Medical Sciences, Beijing 100020, China. Email:zhanghuibo1972@aliyun.com.
Abstract
OBJECTIVE: To explore the diagnostic value of 3.0T MRI in neurogenic tumor of soft tissue in the extremities. METHODS: The MRI appearance of 17 neurogenic tumors with pathological confirmation was retrospectively analyzed. Various imaging characteristics of tumors were evaluated and different imaging findings were compared. The diagnosis value of each MRI features was evaluated with receiver-operating-characteristics (ROC) analysis. RESULTS: In the benign tumors significant differences between neurilemmoma and neurofibromas were noted for the position (P = 0.044). Heterogenicity on T(2)-weighted fat suppression images was also significant in differentiating between neurilemmoma and neurofibromas ( P = 0.020) . The shape of tumors, maximum length of tumor short diameter, edem around masses, relationship with adjoining fascia had the best discriminatory ability. The ROC analysis yield the area under curve (AUC) of them was 0.967 (P = 0.037), 0.923 (P = 0.048) , 0.981 (P = 0.034) , 0.981 (P = 0.034), respectively. CONCLUSION: If the neurogenic tumors of soft tissue in the extremities had one or several features of these characteristics (irregular margin, big volume, edem around masses, aggressive behavior with adjoining fascia) on 3.0T MRI, they had more possibility to be malignant. T(2)-weighted fat suppression series on 3.0TMRI was very important for discrimination of tumor histological characteristics.
OBJECTIVE: To explore the diagnostic value of 3.0T MRI in neurogenic tumor of soft tissue in the extremities. METHODS: The MRI appearance of 17 neurogenic tumors with pathological confirmation was retrospectively analyzed. Various imaging characteristics of tumors were evaluated and different imaging findings were compared. The diagnosis value of each MRI features was evaluated with receiver-operating-characteristics (ROC) analysis. RESULTS: In the benign tumors significant differences between neurilemmoma and neurofibromas were noted for the position (P = 0.044). Heterogenicity on T(2)-weighted fat suppression images was also significant in differentiating between neurilemmoma and neurofibromas ( P = 0.020) . The shape of tumors, maximum length of tumor short diameter, edem around masses, relationship with adjoining fascia had the best discriminatory ability. The ROC analysis yield the area under curve (AUC) of them was 0.967 (P = 0.037), 0.923 (P = 0.048) , 0.981 (P = 0.034) , 0.981 (P = 0.034), respectively. CONCLUSION: If the neurogenic tumors of soft tissue in the extremities had one or several features of these characteristics (irregular margin, big volume, edem around masses, aggressive behavior with adjoining fascia) on 3.0T MRI, they had more possibility to be malignant. T(2)-weighted fat suppression series on 3.0TMRI was very important for discrimination of tumor histological characteristics.