| Literature DB >> 24730463 |
Amina Boucherif1, Qing-Qing Yang, Qiang Wang, Jia-Rong Chen, Liang-Qiu Lu, Wen-Jing Xiao.
Abstract
An asymmetric synthesis of epoxyoxindoles from isatins has been developed by employing chiral sulfur ylides generated in situ from camphor-derived sulfonium salts. This reaction allows an efficient access to enantioenriched spiro-epoxyoxindoles under mild reaction conditions, featuring high yields and excellent enantio- and diastereoselectivities.Entities:
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Year: 2014 PMID： 24730463 DOI： 10.1021/jo5003856
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354