Literature DB >> 2472996

A case of gallbladder carcinoma producing both alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA).

Y Sugaya1, H Sugaya, Y Kuronuma, T Hisauchi, T Harada.   

Abstract

A 73-year-old woman with gallbladder carcinoma infiltrating to the liver presenting high serum values of AFP and CEA was reported. Serum values of AFP and CEA were remarkably high (165,000 ng/ml and 1,070 ng/ml). Immunohistochemically the tumor cells were stained for AFP and CEA by the PAP method. Serum AFP subfraction was analyzed by crossed immunoaffinoelectrophoresis with lentil lectin and concanavalin A, which showed most of the serum AFP bound to both lentil lectin and concanavalin A. As a case of gallbladder carcinoma presenting a high serum value of AFP is rare, it may imply a diagnostic challenge.

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Year:  1989        PMID: 2472996     DOI: 10.1007/bf02774332

Source DB:  PubMed          Journal:  Gastroenterol Jpn        ISSN: 0435-1339


  20 in total

1.  Differential reactivity of alpha-fetoprotein with lectins and its usefulness in the diagnosis of various liver diseases.

Authors:  P K Buamah; C Cornell; A J Cassells-Smith; A W Skillen
Journal:  Clin Chim Acta       Date:  1987-09-15       Impact factor: 3.786

2.  Synthesis of -fetoprotein by liver, yolk sac, and gastrointestinal tract of the human conceptus.

Authors:  D Gitlin; A Perricelli; G M Gitlin
Journal:  Cancer Res       Date:  1972-05       Impact factor: 12.701

3.  Alpha-fetoprotein in patients of gastric carcinoma with or without liver metastasis.

Authors:  H Kuriyama; S Noguchi; J Okamura; F Murakami; D Jinnal
Journal:  Med J Osaka Univ       Date:  1972-12

4.  [Existence of alpha feto protein during gastric-origin secondary cancer of the liver].

Authors:  J Bourreille; P Metayer; F Sauger; F Matray; A Fondimare
Journal:  Presse Med       Date:  1970-06-06       Impact factor: 1.228

5.  [Carcinoembryonic antigen, alpha-fetoprotein and human chorionic gonadotropin producing gastric cancer].

Authors:  T Honda; S Katusima; Y Tokuda; K Matuda; Y Oonisi; T Taniguchi; J Oomoto; Y Kawaguchi
Journal:  Nihon Naika Gakkai Zasshi       Date:  1984-04

6.  A case of gastric carcinoma whose serum was positive for alpha-fetoprotein, variant alkaline phosphatase and CEA (author's transl).

Authors:  K Okita; K I Noda; M Hayakawa; T Kodama; T Takenami; Y Fukumoto; R Fujii; K Kawahara; T Date; Y Okazaki; H Nishimura; T Takemoto
Journal:  Nihon Shokakibyo Gakkai Zasshi       Date:  1978-02

7.  [A case of alpha-fetoprotein strongly positive cholecystic cancer associated with porcelain gallbladder (author's transl)].

Authors:  K Miyasaka; T Kabashima; H Hamaguchi; T Hanada; K Mitsunaga; S Maejima; M Hatano
Journal:  Rinsho Hoshasen       Date:  1978-05

8.  Serum alpha-fetoprotein in patients with neoplasms of the gastrointestinal tract.

Authors:  K R McIntire; T A Waldmann; C G Moertel; V L Go
Journal:  Cancer Res       Date:  1975-04       Impact factor: 12.701

9.  Differential reactivity of alpha-fetoprotein with lectins and evaluation of its usefulness in the diagnosis of hepatocellular carcinoma.

Authors:  Y Aoyagi; Y Suzuki; M Isemura; K Soga; T Ozaki; T Ichida; K Inoue; H Sasaki; F Ichida
Journal:  Gan       Date:  1984-09

10.  Specific carcinoembryonic antigens of the human digestive system.

Authors:  P Gold; S O Freedman
Journal:  J Exp Med       Date:  1965-09-01       Impact factor: 14.307

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  5 in total

1.  Alpha-fetoprotein-producing carcinoma of the gallbladder.

Authors:  M Watanabe; Y Hori; T Nojima; H Kato; K Taketa; S Isogawa; K Yokoyama; S Nakagawa
Journal:  Dig Dis Sci       Date:  1993-03       Impact factor: 3.199

2.  Alpha-Fetoprotein-Secreting Gallbladder Carcinoma: a Case Report.

Authors:  Guray Akturk; Ozgul Sagol; Tarkan Unek; Mucahit Ozbilgin; Tufan Egeli; Sedat Karademir; Funda Obuz; Ibrahim Kemal Astarcioglu
Journal:  J Gastrointest Cancer       Date:  2018-12

3.  Elevated serum alpha-fetoprotein in a patient with undifferentiated carcinoma of the gall bladder.

Authors:  W K Ng; W F Ng
Journal:  J Clin Pathol       Date:  1995-11       Impact factor: 3.411

4.  Clinicopathological characteristics of alpha-fetoprotein-producing gastric cancer.

Authors:  Huan Chun; Sung Joon Kwon
Journal:  J Gastric Cancer       Date:  2011-03-31       Impact factor: 3.720

5.  Biochemical characterization of alpha-fetoprotein and other serum proteins produced by a uterine endometrial adenocarcinoma.

Authors:  Y Koyama; K Taketa; M Azuma; R Yamamoto; S Fujimoto; S Nishi
Journal:  Jpn J Cancer Res       Date:  1996-06
  5 in total

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