Literature DB >> 24728938

Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults.

Celia F Hybels1, Linda K George2, Dan G Blazer2, Carl F Pieper2, Harvey J Cohen2, Harold G Koenig3.   

Abstract

OBJECTIVE: The aim of this study was to examine inflammation and coagulation, which are positively linked to disability and inversely linked to increased religious attendance, as mediators in the cross-sectional relationships between religious attendance and functional status.
METHOD: Frequency of attendance and limitations in basic activities of daily living (ADLs), instrumental activities (IADLs), and mobility were assessed in 1,423 elders.
RESULTS: More frequent attendance was associated with fewer ADL, IADL, and mobility limitations, and with lower levels of inflammation and coagulation including interleukin-6, soluble vascular cell adhesion molecule, and D-dimer. Inflammation and coagulation partially mediated the associations between attendance and function. Eight percent of the effect of attendance on ADL (p = .014), 5% of the effect on IADL (p = .003), and 8% of the effect on mobility (p = .001) limitations were due to inflammation and coagulation. DISCUSSION: Relationships between attendance and function may be due in part to lower levels of inflammation and coagulation among elders who attend services.
© The Author(s) 2014.

Entities:  

Keywords:  aging; coagulation; functional status; inflammation; religion

Year:  2014        PMID: 24728938      PMCID: PMC4193946          DOI: 10.1177/0898264314527479

Source DB:  PubMed          Journal:  J Aging Health        ISSN: 0898-2643


  44 in total

1.  Religion, health, and psychological well-being in older adults: findings from three national surveys.

Authors:  J S Levin; L M Chatters
Journal:  J Aging Health       Date:  1998-11

2.  Religiousness and Longitudinal Trajectories in Elders' Functional Status.

Authors:  Nan Sook Park; David L Klemmack; Lucinda L Roff; Michael W Parker; Harold G Koenig; Patricia Sawyer; Richard M Allman
Journal:  Res Aging       Date:  2008

3.  Developing a summary measure of medical status.

Authors:  G G Fillenbaum; J K Leiss; C F Pieper; H J Cohen
Journal:  Aging (Milano)       Date:  1998-10

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Authors:  H J Cohen; C F Pieper; T Harris; K M Rao; M S Currie
Journal:  J Gerontol A Biol Sci Med Sci       Date:  1997-07       Impact factor: 6.053

5.  Attendance at religious services, interleukin-6, and other biological parameters of immune function in older adults.

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Journal:  Int J Psychiatry Med       Date:  1997       Impact factor: 1.210

6.  The stress process.

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Journal:  J Health Soc Behav       Date:  1981-12

7.  Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons.

Authors:  David B Reuben; Anna I Cheh; Tamara B Harris; Luigi Ferrucci; John W Rowe; Russell P Tracy; Teresa E Seeman
Journal:  J Am Geriatr Soc       Date:  2002-04       Impact factor: 5.562

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Authors:  E L Idler; S V Kasl
Journal:  J Gerontol B Psychol Sci Soc Sci       Date:  1997-11       Impact factor: 4.077

9.  Religious involvement and 6-year course of depressive symptoms in older Dutch citizens: results from the Longitudinal Aging Study Amsterdam.

Authors:  Arjan W Braam; Erik Hein; Dorly J H Deeg; Jos W R Twisk; Aartjan T F Beekman; Willem Van Tilburg
Journal:  J Aging Health       Date:  2004

10.  Association of interleukin-6 and other biologic variables with depression in older people living in the community.

Authors:  A N Dentino; C F Pieper; M K Rao; M S Currie; T Harris; D G Blazer; H J Cohen
Journal:  J Am Geriatr Soc       Date:  1999-01       Impact factor: 5.562

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  1 in total

1.  Religiosity/Spirituality and Physiological Markers of Health.

Authors:  Eric C Shattuck; Michael P Muehlenbein
Journal:  J Relig Health       Date:  2020-04
  1 in total

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