Literature DB >> 24727430

Modelling PowerPlex® Y stutter and artefacts.

Jo-Anne Bright1, James M Curran2, John S Buckleton3.   

Abstract

We have investigated the suitability of models used to predict expected stutter ratios and their variance developed for autosomal STR markers for application to Y STR markers. Models for expected back stutter, double back stutter, and forward stutter ratios for all loci in the PowerPlex(®) Y multiplex and the heights of stutter-like artefacts at DYS19 and DYS385 are proposed. The longest uninterrupted stretch of repeats within an allele (LUS), marker and parent allele height was investigated as explanatory variables for stutter ratio and artefact height. The models are intended to be used within an expert system employing a continuous method of DNA interpretation.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Keywords:  Analysis artefacts; DNA interpretation; Stutter; Y STR profiles

Mesh:

Substances:

Year:  2014        PMID: 24727430     DOI: 10.1016/j.fsigen.2014.03.007

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  2 in total

1.  Yfiler Plus population samples and dilution series: stutters, analytic thresholds, and drop-out probabilities.

Authors:  Mikkel Meyer Andersen; Helle Smidt Mogensen; Poul Svante Eriksen; Niels Morling
Journal:  Int J Legal Med       Date:  2017-03-07       Impact factor: 2.686

2.  Flanking Variation Influences Rates of Stutter in Simple Repeats.

Authors:  August E Woerner; Jonathan L King; Bruce Budowle
Journal:  Genes (Basel)       Date:  2017-11-17       Impact factor: 4.096

  2 in total

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